Nitric oxide therapy for diabetic wound healing

MJ Malone‐Povolny, SE Maloney… - Advanced healthcare …, 2019 - Wiley Online Library
Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate
inflammation and eradicate bacterial infections. Two broad strategies exist to utilize NO for …

Role of nitric oxide in wound repair

MB Witte, A Barbul - The American Journal of Surgery, 2002 - Elsevier
After injury, wound healing is essential for recovery of the integrity of the body. It is a
complex, sequential cascade of events. Nitric oxide (NO) is a small radical, formed from the …

Redox signals in wound healing

CK Sen, S Roy - Biochimica et Biophysica Acta (BBA)-General Subjects, 2008 - Elsevier
Physical trauma represents one of the most primitive challenges that threatened survival.
Healing a problem wound requires a multi-faceted comprehensive approach. First and …

Effects of nitric oxide releasing poly (vinyl alcohol) hydrogel dressings on dermal wound healing in diabetic mice

KSB Masters, SJ Leibovich, P Belem… - Wound Repair and …, 2002 - Wiley Online Library
Healing of chronic wounds such as diabetic foot ulcers is a significant clinical problem.
Methods of accelerating healing in these difficult lower extremity sites include use of growth …

Recent progress in gene delivery using non-viral transfer complexes

WT Godbey, AG Mikos - Journal of Controlled Release, 2001 - Elsevier
The delivery of genetic material into cells is a field that is expanding very rapidly. Non-viral
delivery methods, especially ones that focus on the use of chemical agents complexed with …

Therapeutic role of nitric oxide as emerging molecule

S Kumar, RK Singh, TR Bhardwaj - Biomedicine & Pharmacotherapy, 2017 - Elsevier
NO has many physiological roles; in inflammation, pain, rheumatoid arthritis, immune
system, gastroprotection, as antioxidant and reported to be a free radical scavenger …

Nitric oxide and wound healing

M Rizk, MB Witte, A Barbul - World journal of surgery, 2004 - Springer
Nitric oxide is a short-lived free radical that acts at the molecular, cellular, and physiologic
level. Since its discovery almost 20 years ago it has proven itself as an important element in …

Enhancing microcirculation on multitriggering manner facilitates angiogenesis and collagen deposition on wound healing by photoreleased NO from hemin …

CH Su, WP Li, LC Tsao, LC Wang, YP Hsu, WJ Wang… - ACS …, 2019 - ACS Publications
A deficiency of nitric oxide (NO) supply has been found to impair wound healing. The
exogenous topical delivery of NO is a promising approach to enhance vasodilation and …

Nitric oxide-releasing chitosan film for enhanced antibacterial and in vivo wound-healing efficacy

JO Kim, JK Noh, RK Thapa, N Hasan, M Choi… - International journal of …, 2015 - Elsevier
Nitric oxide (NO) is a promising therapeutic agent with antibacterial and wound-healing
properties. However, the gaseous state and short half-life of NO necessitate a formulation …

Electrospun nitric oxide releasing bandage with enhanced wound healing

A Lowe, J Bills, R Verma, L Lavery, K Davis… - Acta biomaterialia, 2015 - Elsevier
Research has shown that nitric oxide (NO) enhances wound healing. The incorporation of
NO into polymers for medical materials and surgical devices has potential benefits for many …