RNA granules: functional compartments or incidental condensates?

A Putnam, L Thomas, G Seydoux - Genes & development, 2023 - genesdev.cshlp.org
RNA granules are mesoscale assemblies that form in the absence of limiting membranes.
RNA granules contain factors for RNA biogenesis and turnover and are often assumed to …

Mechanisms of germ cell specification across the metazoans: epigenesis and preformation

CG Extavour, M Akam - 2003 - journals.biologists.com
Germ cells play a unique role in gamete production, heredity and evolution. Therefore, to
understand the mechanisms that specify germ cells is a central challenge in developmental …

Direct observation of translational activation by a ribonucleoprotein granule

R Chen, W Stainier, J Dufourt, M Lagha… - Nature Cell …, 2024 - nature.com
Biomolecular condensates organize biochemical processes at the subcellular level and can
provide spatiotemporal regulation within a cell. Among these, ribonucleoprotein (RNP) …

Differentiating protein-coding and noncoding RNA: challenges and ambiguities

ME Dinger, KC Pang, TR Mercer… - PLoS computational …, 2008 - journals.plos.org
The assumption that RNA can be readily classified into either protein-coding or non-protein–
coding categories has pervaded biology for close to 50 years. Until recently, discrimination …

RNA granules in germ cells

E Voronina, G Seydoux… - Cold Spring …, 2011 - cshperspectives.cshlp.org
“Germ granules” are cytoplasmic, nonmembrane-bound organelles unique to germline.
Germ granules share components with the P bodies and stress granules of somatic cells, but …

[HTML][HTML] Regulation of zygotic gene expression in Drosophila primordial germ cells

M Van Doren, AL Williamson, R Lehmann - Current Biology, 1998 - cell.com
Activation of the zygotic genome is a prerequisite for the transition from maternal to zygotic
control of development. The onset of zygotic transcription has been well studied in somatic …

Transient increase in obese gene expression after food intake or insulin administration

R Saladin, P De Vos, M Guerre-Millot, A Leturque… - Nature, 1995 - nature.com
OBESITY is a disorder of energy balance, indicating a chronic disequilibrium between
energy intake and expenditure1. Recently, the mouse ob gene2, and subsequently its …

[HTML][HTML] Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development

M Bose, M Lampe, J Mahamid, A Ephrussi - Cell, 2022 - cell.com
Asymmetric localization of oskar ribonucleoprotein (RNP) granules to the oocyte posterior is
crucial for abdominal patterning and germline formation in the Drosophila embryo. We show …

[图书][B] The insect ovary: ultrastructure, previtellogenic growth and evolution

J Büning - 1994 - books.google.com
This book will give an overview of insect ovaries, showing the diversities and the common
traits in egg growth processes. The idea to write this book developed while looking at the …

An RNA biosensor for imaging the first round of translation from single cells to living animals

JM Halstead, T Lionnet, JH Wilbertz, F Wippich… - Science, 2015 - science.org
Analysis of single molecules in living cells has provided quantitative insights into the kinetics
of fundamental biological processes; however, the dynamics of messenger RNA (mRNA) …