MicroRNAs (miRNAs) are conserved, short, non-coding RNAs that play a crucial role in the
post-transcriptional regulation of gene expression. They have been implicated in the …

Mitochondria are important cellular organelles involved in many different functions, from
energy generation and fatty acid oxidation to cell death regulation and immune responses …

Abstract Bax inhibitor-1 (BI1) conveys anti-apoptotic signals for mitochondria while prohibitin
2 (PHB2) is implicated in sustaining mitochondrial morphology and function. However, their …

Transactive response DNA-binding protein of 43 kDa (TDP-43) functions as a
heterogeneous nuclear ribonucleoprotein and is the major pathological protein in …

Prohibitins (PHBs) are a highly conserved class of proteins and have an essential role in
transcription, epigenetic regulation, nuclear signaling, mitochondrial structural integrity, cell …

Prohibitins (PHBs) are a class of highly evolutionarily conserved proteins that widely
distribute in prokaryotes and eukaryotes. PHBs function in cell growth and proliferation or …

Background and purpose: Mitophagy plays a significant role in the progression of diabetic
nephropathy (DN), although the regulatory mechanisms remain unclear. Recently …

Heart aging is characterized by left ventricular hypertrophy and diastolic dysfunction, which
in turn induces a variety of cardiovascular diseases. There is still no therapeutic drug to …

Autophagy is a catabolic process involving vacuolar sequestration of intracellular
components and their targeting to lysosomes for degradation, thus supporting nutrient …

Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized
mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways …