Nanogenerator-based sensors for energy harvesting from cardiac contraction

EA Al-Suhaimi, MA Aljafary, TM Alfareed… - Frontiers in Energy …, 2022 - frontiersin.org
Biomedical electric devices provide great assistance for health and life quality. However,
their maintainable need remains a serious issue for the restricted duration of energy storage …

Mechanisms underlying electro-mechanical dysfunction in the Zucker diabetic fatty rat heart: a model of obesity and type 2 diabetes

A Sultan, J Singh, FC Howarth - Heart Failure Reviews, 2020 - Springer
Diabetes mellitus (DM) is a major and worsening global health problem, currently affecting
over 450 million people and reducing their quality of life. Type 2 diabetes mellitus (T2DM) …

Leptin is not essential for obesity-associated hypertension

J von Schnurbein, J Manzoor, S Brandt, F Denzer… - Obesity facts, 2019 - karger.com
Abstract Background and Objective: Hyperleptinemia is supposed to play a causal role in
the development of obesity-associated hypertension, possibly via increased sympathetic …

The nutrient sensing pathways FoxO1/3 and mTOR in the heart are coordinately regulated by central leptin through PPARβ/δ. Implications in cardiac remodeling

B Rubio, C Mora, C Pintado, L Mazuecos, A Fernández… - Metabolism, 2021 - Elsevier
Background Cardiovascular disease in obese individuals with type 2 diabetes is often
associated with hyperleptinemia and leptin resistance, while other studies support that leptin …

Cardiovascular and metabolic consequences of the association between chronic stress and high-fat diet in rats

BB Simas, EA Nunes, CC Crestani, GF Speretta - Stress, 2018 - Taylor & Francis
Obesity and chronic stress are considered independent risk factors for the development of
cardiovascular diseases and changes in autonomic system activity. However, the …

[HTML][HTML] PM2. 5 induced cardiac hypertrophy via CREB/GSK3b/SOS1 pathway and metabolomics alterations

KL Li, YC Lin - Oncotarget, 2018 - ncbi.nlm.nih.gov
The particle matter with diameter less 2.5μm (PM2. 5) easier to adsorb toxic substance, and
interfere with pulmonary gas exchange. In this study, cardioprotective effects of low …

[HTML][HTML] The adipose-neural axis is involved in epicardial adipose tissue-related cardiac arrhythmias

Y Fan, S Huang, S Li, B Wu, Q Zhao, L Huang… - Cell Reports …, 2024 - cell.com
Dysfunction of the sympathetic nervous system and increased epicardial adipose tissue
(EAT) have been independently associated with the occurrence of cardiac arrhythmia …

A potential adverse role for leptin and cardiac leptin receptor in the right ventricle in pulmonary arterial hypertension: effect of metformin is BMPR2 mutation-specific

M Talati, E Brittain, V Agrawal, N Fortune… - Frontiers in …, 2023 - frontiersin.org
Introduction Pulmonary arterial hypertension is a fatal cardiopulmonary disease. Leptin, a
neuroendocrine hormone released by adipose tissue, has a complex relationship with …

[HTML][HTML] The association between leptin and subclinical cardiovascular disease explained by body fat: Observational and Mendelian randomization analyses

T Christen, R de Mutsert, RAJ Smit, KW van Dijk… - Nutrition, Metabolism …, 2023 - Elsevier
Background and aims Leptin has been associated with adverse effects on cardiovascular
disease, but the effect of confounding by body fat in these associations remains unclear. To …

The Prevalence of Bradycardia 12 Years After Roux-en-Y Gastric Bypass for Severe Obesity

S Brudeseth, J Sandvik, S Nymo, G Johnsen… - Obesity Surgery, 2024 - Springer
Purpose The aim was to describe the frequency of bradycardia 12 years after Roux-en-Y
gastric bypass (RYGB), relations to weight loss, patient characteristics, and the clinical …