[HTML][HTML] Immune determinants of endometrial receptivity: a biological perspective

SA Robertson, LM Moldenhauer, ES Green, AS Care… - Fertility and sterility, 2022 - Elsevier
Immune cells are essential for endometrial receptivity to embryo implantation and early
placental development. They exert tissue-remodeling and immune regulatory roles—acting …

The Impacts of Inflammatory and Autoimmune Conditions on the Endometrium and Reproductive Outcomes

I Cuadrado-Torroglosa, JA García-Velasco… - Journal of Clinical …, 2024 - mdpi.com
Background: A healthy pregnancy begins with an adequate endometrial state, even before
the arrival of a blastocyst. Proper endometrial priming and the development of a tolerogenic …

[HTML][HTML] Use of the endometrial receptivity array to guide personalized embryo transfer after a failed transfer attempt was associated with a lower cumulative and per …

M Cozzolino, P Diáz-Gimeno, A Pellicer, N Garrido - Fertility and Sterility, 2022 - Elsevier
Objective To determine whether personalized embryo transfer (pET) guided by endometrial
receptivity array (ERA) test improves reproductive outcomes for fresh embryo transfers …

[HTML][HTML] Regulatory T cells are paramount effectors in progesterone regulation of embryo implantation and fetal growth

ES Green, LM Moldenhauer, HM Groome, DJ Sharkey… - JCI insight, 2023 - ncbi.nlm.nih.gov
Progesterone (P4) is essential for embryo implantation, but the extent to which the pro-
gestational effects of P4 depend on the maternal immune compartment is unknown. Here …

Use of 'omics for endometrial timing: the cycle moves on

JD Aplin, A Stevens - Human Reproduction, 2022 - academic.oup.com
For some years, the prospect of precise and personalized timing of the endometrial cycle for
optimal embryo replacement has been held out as a potential solution to low implantation …

Commercially available molecular approaches to evaluate endometrial receptivity: a systematic review and critical analysis of the literature

E Maziotis, T Kalampokas, P Giannelou, S Grigoriadis… - Diagnostics, 2022 - mdpi.com
Despite the advances in the field of reproductive medicine, implantation failure represents a
challenging condition affecting 10–30% of patients subjected to in vitro fertilization (IVF) …

The endometrial transcriptome of infertile women with and without implantation failure

BN Bui, V Kukushkina, A Meltsov… - Acta obstetricia et …, 2024 - Wiley Online Library
Introduction Implantation failure after transferring morphologically “good‐quality” embryos in
in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) may be explained by impaired …

Targeted gene expression profiling for accurate endometrial receptivity testing

A Meltsov, M Saare, H Teder, P Paluoja, RK Arffman… - Scientific Reports, 2023 - nature.com
Expressional profiling of the endometrium enables the personalised timing of the window of
implantation (WOI). This study presents and evaluates a novel analytical pipeline based on …

Predicting risk of endometrial failure: a biomarker signature that identifies a novel disruption independent of endometrial timing in patients undergoing hormonal …

P Diaz-Gimeno, P Sebastian-Leon, K Spath… - Fertility and …, 2024 - Elsevier
Objective To propose a new gene expression signature that identifies endometrial
disruptions independent of endometrial luteal phase timing and predicts if patients are at risk …

The impact of endometrial scratch performed in mid-luteal phase on the endometrium whole genome transcriptomic profiles in following menstrual cycle

Y Tian, J Huang, CC Wang, H Lin, X Huang… - Human …, 2023 - Taylor & Francis
The value of endometrial scratch in women with recurrent embryo transfer has been
controversial. Endometrial scratch is often performed in the mid-luteal phase of the cycle …