Mathematical models of skin permeability play an important role in various fields including
prediction of transdermal drug delivery and assessment of dermal exposure to industrial …

Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

Monitoring blood glucose levels for diabetic patients is critical to achieve tight glycaemic
control. As none of the current antidiabetic treatments restore lost functional β-cell mass in …

Purpose To develop models for rabbit, monkey, and human that enable prediction of the
clearance after intravitreal (IVT) injections in one species from experimental results obtained …

Microneedles (MNs) as a novel transdermal drug delivery system have shown great
potential for therapeutic and disease diagnosis applications by continually providing …

In recent years, the combination of computational modeling and experiments has become a
useful tool that is proving increasingly powerful for explaining biological complexity. As …

The development in the field of pharmaceutical dosage forms results in the discovery of
additional highly sophisticated drug delivery systems that allow maintaining a constant level …

Each individual's skin has its own features, such as strength, elasticity, or permeability to
drugs, which limits the effectiveness of one-size-fits-all approaches typically found in …

Molecular transport through a composite multilayer membrane is a central process in
transdermal drug delivery (TDD). Classical Fickean approach treats skin as a pseudo …

Transdermal fentanyl patches are an effective alternative to the sustained release of oral
morphine for chronic pain management. Due to the narrow therapeutic range of fentanyl, the …