Increasing the complexity of lipoprotein characterization for cardiovascular risk in type 2 diabetes

M Guardiola, P Rehues, N Amigó… - European Journal of …, 2024 - Wiley Online Library
The burden of cardiovascular disease is particularly high among individuals with diabetes,
even when LDL cholesterol is normal or within the therapeutic target. Despite this …

ApoC-III proteoforms are associated with better lipid, inflammatory, and glucose profiles independent of total apoC-III

P Rehues, J Girona, M Guardiola, E Ozcariz… - Cardiovascular …, 2024 - Springer
Apolipoprotein (apo) C-III is involved in several processes that increase triglyceride levels,
inflammation, and insulin resistance. Four of its proteoforms have been the focus of several …

SGLT2 inhibition, high-density lipoprotein, and kidney function: a mendelian randomization study

Z Wang, J Wei, W Zhao, R Shi, Y Zhu, X Li… - Lipids in Health and …, 2024 - Springer
Background Sodium-glucose cotransporter 2 (SGLT2) inhibition is recognized for its evident
renoprotective benefits in diabetic renal disease. Recent data suggest that SGLT2 inhibition …

[HTML][HTML] Causal Association between Circulating Metabolites and Dementia: A Mendelian Randomization Study

HM Li, CS Qiu, LY Du, XL Tang, DQ Liao, ZY Xiong… - Nutrients, 2024 - mdpi.com
The causal association of circulating metabolites with dementia remains uncertain. We
assessed the causal association of circulating metabolites with dementia utilizing Mendelian …

Association of serum uric acid to high-density lipoprotein cholesterol ratio with all-cause and cardiovascular mortality in patients with diabetes or prediabetes: a …

X Lai, T Chen - Frontiers in Endocrinology, 2024 - frontiersin.org
Background and aims The serum uric acid (UA) to high-density lipoprotein cholesterol (HDL-
C) ratio (UHR) is a novel biomarker that indicates inflammation and metabolic disorders …

Pleiotropic functions and clinical importance of circulating HDL-PON1 complex.

A Mahrooz - Advances in Clinical Chemistry, 2024 - europepmc.org
High density lipoprotein (HDL) functions are mostly mediated through a complex proteome,
particularly its enzymes. HDL can provide a scaffold for the assembly of several proteins that …

[PDF][PDF] Increasing the complexity of lipoprotein characterization for cardiovascular risk in type 2 diabetes

M Botana, JA Gimeno-Orna, J Girona… - 2024 - researchgate.net
The burden of cardiovascular disease is particularly high among individuals with diabetes,
even when LDL cholesterol is normal or within the therapeutic target. Despite this …