Fluorescence image-guided tumour surgery
Intraoperative fluorescent imaging can provide real-time identification of tumours, lymph
nodes, nerves and other healthy and malignant tissues during oncological surgery …
nodes, nerves and other healthy and malignant tissues during oncological surgery …
Current trends and key considerations in the clinical translation of targeted fluorescent probes for intraoperative navigation
The rapid development of fluorescence imaging for intraoperative navigation has spurred
further development of targeted fluorescent probes in the past decade. Only a few …
further development of targeted fluorescent probes in the past decade. Only a few …
Self‐sacrificially degradable pseudo‐semiconducting polymer nanoparticles that integrate NIR‐II fluorescence bioimaging, photodynamic immunotherapy, and photo …
Semiconducting polymers (SP) hold great promise for cancer phototherapy due to their
excellent optical properties; however, their clinical application is still hampered by their poor …
excellent optical properties; however, their clinical application is still hampered by their poor …
Fluorescence lifetime of injected indocyanine green as a universal marker of solid tumours in patients
R Pal, TM Lwin, M Krishnamoorthy… - Nature Biomedical …, 2023 - nature.com
The surgical resection of solid tumours can be enhanced by fluorescence-guided imaging.
However, variable tumour uptake and incomplete clearance of fluorescent dyes reduces the …
However, variable tumour uptake and incomplete clearance of fluorescent dyes reduces the …
Bioorthogonally activatable cyanine dye with torsion-induced disaggregation for in vivo tumor imaging
X Zhang, J Gao, Y Tang, J Yu, SS Liew, C Qiao… - Nature …, 2022 - nature.com
Advancement of bioorthogonal chemistry in molecular optical imaging lies in expanding the
repertoire of fluorophores that can undergo fluorescence signal changes upon …
repertoire of fluorophores that can undergo fluorescence signal changes upon …
Cell surface-localized imaging and sensing
Systematically dissecting the molecular basis of the cell surface as well as its related
biological activities is considered as one of the most cutting-edge fields in fundamental …
biological activities is considered as one of the most cutting-edge fields in fundamental …
Annexin animal models—from fundamental principles to translational research
Routine manipulation of the mouse genome has become a landmark in biomedical
research. Traits that are only associated with advanced developmental stages can now be …
research. Traits that are only associated with advanced developmental stages can now be …
Repurposing molecular imaging and sensing for cancer image–guided surgery
Gone are the days when medical imaging was used primarily to visualize anatomic
structures. The emergence of molecular imaging (MI), championed by radiolabeled 18F …
structures. The emergence of molecular imaging (MI), championed by radiolabeled 18F …
First clinical results of fluorescence lifetime-enhanced tumor imaging using receptor-targeted fluorescent probes
Purpose: Fluorescence molecular imaging, using cancer-targeted near infrared (NIR)
fluorescent probes, offers the promise of accurate tumor delineation during surgeries and …
fluorescent probes, offers the promise of accurate tumor delineation during surgeries and …
Molecular Engineering of Sulfone-Xanthone Chromophore for Enhanced Fluorescence Navigation
H Zhang, FF Xiang, YZ Liu, YJ Chen, DH Zhou, YH Liu… - JACS Au, 2023 - ACS Publications
Enriching the palette of high-performance fluorescent dyes is vital to support the frontier of
biomedical imaging. Although various rhodamine skeletons remain the premier type of small …
biomedical imaging. Although various rhodamine skeletons remain the premier type of small …