Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is the label given to a
syndrome that can include long-term flu-like symptoms, profound fatigue, trouble …

Macrophages play a key role in the pathophysiology of rheumatoid arthritis (RA). Notably,
positive correlations have been reported between synovial macrophage infiltration and …

Abstract Gulf War Illness (GWI) is a chronic disorder affecting approximately 30% of the
veterans who served in the 1991 Gulf War. It is characterised by a constellation of symptoms …

Objective Cortical spreading depression (CSD) underlies the neurobiology of migraine with
aura (MWA). Animal studies reveal networks of microvessels linking brain–meninges–bone …

Tumor associated macrophages (TAM) are key players in the cancer microenvironment.
Molecular imaging modalities such as MRI and PET can be used to track and monitor TAM …

Myocardial infarction (MI) is one of the leading causes of death worldwide, and inflammation
is central to tissue response and patient outcomes. The 18-kDa translocator protein (TSPO) …

Non-invasive imaging of arthritis activity in rheumatoid arthritis (RA) patients using
macrophage PET holds promise for early diagnosis and therapeutic response monitoring …

Abstract Background Cyclooxygenase-2 (COX-2), which is rapidly upregulated by
inflammation, is a key enzyme catalyzing the rate-limiting step in the synthesis of several …

Arthritis and other rheumatic disorders are very frequent in the general population and
responsible for a huge physical and disability burden to affected patients as well as a major …

Tumor-associated macrophages (TAMs), the most abundant inflammatory cell group in the
tumor microenvironment, play an essential role in tumor immune regulation. The infiltration …