Diabetes modulates MicroRNAs 29b-3p, 29c-3p, 199a-5p and 532-3p expression in muscle: possible role in GLUT4 and HK2 repression

JV Esteves, CY Yonamine, DC Pinto-Junior… - Frontiers in …, 2018 - frontiersin.org
The reduced expression of solute carrier family 2, facilitated glucose transporter member 4
(GLUT4) and hexokinase-2 (HK2) in skeletal muscle participates in insulin resistance of …

Insulin resistance of pregnancy involves estrogen-induced repression of muscle GLUT4

RPDA Barros, A Morani, A Moriscot… - Molecular and Cellular …, 2008 - Elsevier
Pregnancy is accompanied by hyperestrogenism, however, the role of estrogens in the
gestational-induced insulin resistance is unknown. Skeletal muscle plays a fundamental role …

[HTML][HTML] Long-term high-fat diet-induced obesity decreases the cardiac leptin receptor without apparent lipotoxicity

AF Nascimento, RAM Luvizotto, AS Leopoldo… - Life sciences, 2011 - Elsevier
Aims Leptin resistance has been associated with cardiac lipotoxicity; however, whether
leptin resistance is a risk factor associated with cardiac lipotoxicity at different time points in …

T3 Rapidly Increases SLC2A4 Gene Expression and GLUT4 Trafficking to the Plasma Membrane in Skeletal Muscle of Rat and Improves Glucose Homeostasis

EL Brunetto, SS Teixeira, G Giannocco, UF Machado… - Thyroid, 2012 - liebertpub.com
Background: Glucose transporter 4 (GLUT4) is highly expressed in muscle and fat tissue,
where triiodothyronine (T3) induces solute carrier family 2 facilitated glucose transporter …

Na+-glucose cotransporter SGLT1 protein in salivary glands: potential involvement in the diabetes-induced decrease in salivary flow

R Sabino-Silva, HS Freitas, ML Lamers… - Journal of Membrane …, 2009 - Springer
Oral health complications in diabetes include decreased salivary secretion. The SLC5A1
gene encodes the Na+-glucose cotransporter SGLT1 protein, which not only transports …

[PDF][PDF] Molecular Mechanisms of Muscle Glucose Uptake in Response to Resistance Exercise: A Review.

JL dos Santos, SS de Araujo… - Journal of Exercise …, 2017 - asep.org
Lima FB, Marcal AC. Molecular Mechanisms of Muscle Glucose Uptake in Response to
Resistance Exercise: A Review. JEPonline 2017; 20 (4): 200-211. Evidence shows that …

Thyroid hormone improves insulin signaling and reduces the activation of neurodegenerative pathway in the hippocampus of diabetic adult male rats

F Prieto-Almeida, AC Panveloski-Costa, F Crunfli… - Life sciences, 2018 - Elsevier
Aims Diabetes mellitus (DM) and impairments of glucose metabolism and insulin resistance
in the brain have been suggested as a likely etiology of Alzheimer's disease (AD). Studies …

Palmitate-induced Slc2a4/GLUT4 downregulation in L6 muscle cells: evidence of inflammatory and endoplasmic reticulum stress involvement

P Ebersbach-Silva, AC Poletto, A David-Silva… - Lipids in health and …, 2018 - Springer
Background Obesity is strongly associated to insulin resistance, inflammation, and elevated
plasma free fatty acids, but the mechanisms behind this association are not fully …

N-acetylcysteine counteracts adipose tissue macrophage infiltration and insulin resistance elicited by advanced glycated albumin in healthy rats

KS Da Silva, PR Pinto, NT Fabre, DJ Gomes… - Frontiers in …, 2017 - frontiersin.org
Background: Advanced glycation endproducts elicit inflammation. However, their role in
adipocyte macrophage infiltration and in the development of insulin resistance, especially in …

Estrogen receptor 1 agonist PPT stimulates Slc2a4 gene expression and improves insulin-induced glucose uptake in adipocytes

RS Campello, AB Alves-Wagner… - Current Topics in …, 2012 - ingentaconnect.com
Type 2 diabetes mellitus is characterized by disruption in glycemic homeostasis, involving
impaired insulininduced glucose disposal. For that, reduced glucose transporter GLUT4 …