Muscle stem cell isolation and in vitro culture for meat production: A methodological review

KH Choi, JW Yoon, M Kim, HJ Lee… - … reviews in food …, 2021 - Wiley Online Library
Cultured muscle tissue‐based protein products, also known as cultured meat, are produced
through in vitro myogenesis involving muscle stem cell culture and differentiation, and …

Review of technology and materials for the development of cultured meat

DY Lee, SY Lee, JW Jung, JH Kim, DH Oh… - Critical Reviews in …, 2023 - Taylor & Francis
Cultured meat production technology suggested that can solve the problems of traditional
meat production such as inadequate breeding environment, wastewater, methane gas …

Innervation: the missing link for biofabricated tissues and organs

S Das, WJ Gordián-Vélez, HC Ledebur… - NPJ Regenerative …, 2020 - nature.com
Innervation plays a pivotal role as a driver of tissue and organ development as well as a
means for their functional control and modulation. Therefore, innervation should be carefully …

Dysregulation of BRD4 function underlies the functional abnormalities of MeCP2 mutant neurons

Y Xiang, Y Tanaka, B Patterson, SM Hwang, E Hysolli… - Molecular cell, 2020 - cell.com
Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2
(MeCP2), is one of the most prevalent intellectual disorders without effective therapies. Here …

Bioengineering outlook on cultivated meat production

I Pajčin, T Knežić, I Savic Azoulay, V Vlajkov… - Micromachines, 2022 - mdpi.com
Cultured meat (also referred to as cultivated meat or cell-based meat)—CM—is fabricated
through the process of cellular agriculture (CA), which entails application of bioengineering …

Methionine adenosyltransferase2A inhibition restores metabolism to improve regenerative capacity and strength of aged skeletal muscle

N Rajabian, I Ikhapoh, S Shahini, D Choudhury… - Nature …, 2023 - nature.com
We investigate the age-related metabolic changes that occur in aged and rejuvenated
myoblasts using in vitro and in vivo models of aging. Metabolic and signaling experiments …

[HTML][HTML] The roles of growth factors and hormones in the regulation of muscle satellite cells for cultured meat production

SS Ahmad, HJ Chun, K Ahmad, S Shaikh… - Journal of Animal …, 2023 - ncbi.nlm.nih.gov
Cultured meat is a potential sustainable food generated by the in vitro myogenesis of muscle
satellite (stem) cells (MSCs). The self-renewal and differentiation properties of MSCs are of …

Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage

D Kamiya, N Takenaka-Ninagawa, S Motoike… - NPJ Regenerative …, 2022 - nature.com
Mesenchymal stem/stromal cells (MSCs) are adult multipotent stem cells. Here, we induced
MSCs from human induced pluripotent stem cells (iPSCs) via a neural crest cell (NCC) …

Characterization of gelatin hydrogels cross-linked with microbial transglutaminase as engineered skeletal muscle substrates

D Gupta, JW Santoso, ML McCain - Bioengineering, 2021 - mdpi.com
Engineered in vitro models of skeletal muscle are essential for efficiently screening drug
safety and efficacy. However, conventional culture substrates poorly replicate physical …

Ameliorating the hallmarks of cellular senescence in skeletal muscle myogenic progenitors in vitro and in vivo

A Shahini, N Rajabian, D Choudhury, S Shahini… - Science …, 2021 - science.org
Senescence of myogenic progenitors impedes skeletal muscle regeneration. Here, we show
that overexpression of the transcription factor NANOG in senescent myoblasts can overcome …