Codon usage bias

ST Parvathy, V Udayasuriyan, V Bhadana - Molecular biology reports, 2022 - Springer
Codon usage bias is the preferential or non-random use of synonymous codons, a
ubiquitous phenomenon observed in bacteria, plants and animals. Different species have …

Acyl-CoA: diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology

Q Liu, RMP Siloto, R Lehner, SJ Stone… - Progress in lipid …, 2012 - Elsevier
Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …

Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, and Arabidopsis

L Duret, D Mouchiroud - Proceedings of the National …, 1999 - National Acad Sciences
We measured the expression pattern and analyzed codon usage in 8,133, 1,550, and 2,917
genes, respectively, from Caenorhabditis elegans, Drosophila melanogaster, and …

密码子偏性的分析方法及相关研究进展

吴宪明, 吴松锋, 任大明, 朱云平, 贺福初 - 遗传, 2007 - chinagene.cn
密码子偏性是指生物体中编码同一种氨基酸的同义密码子的非均衡使用现象,
由于这一现象与遗传信息的载体分子DNA 和生物功能分子蛋白质相关联 …

Codon usage: nature's roadmap to expression and folding of proteins

E Angov - Biotechnology journal, 2011 - Wiley Online Library
Biomedical and biotechnological research relies on processes leading to the successful
expression and production of key biological products. High‐quality proteins are required for …

Ribosome and transcript copy numbers, polysome occupancy and enzyme dynamics in Arabidopsis

M Piques, WX Schulze, M Höhne, B Usadel… - Molecular systems …, 2009 - embopress.org
Plants are exposed to continual changes in the environment. The daily alternation between
light and darkness results in massive recurring changes in the carbon budget, and leads to …

Gene expression and molecular evolution

H Akashi - Current Opinion in Genetics & Development, 2001 - Elsevier
The combination of complete genome sequence information and estimates of mRNA
abundances have begun to reveal causes of both silent and protein sequence evolution …

Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid region

CC Burns, J Shaw, R Campagnoli, J Jorba… - Journal of …, 2006 - Am Soc Microbiol
We replaced degenerate codons for nine amino acids within the capsid region of the Sabin
type 2 oral poliovirus vaccine strain with corresponding nonpreferred synonymous codons …

The effects of Hill-Robertson interference between weakly selected mutations on patterns of molecular evolution and variation

GAT McVean, B Charlesworth - Genetics, 2000 - academic.oup.com
Associations between selected alleles and the genetic backgrounds on which they are
found can reduce the efficacy of selection. We consider the extent to which such …

DNA helix: the importance of being GC‐rich

AE Vinogradov - Nucleic acids research, 2003 - academic.oup.com
A new explanation for the emergence of heavy (GC‐rich) isochores is proposed, based on
the study of thermostability, bendability, ability to B–Z transition and curvature of the DNA …