The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Background and objective In this present research paper, a mathematical model has been
developed to study myocyte contraction in the human cardiac muscle, using the Land model …

Computational techniques have significantly advanced our understanding of cardiac
electrophysiology, yet they have predominantly concentrated on averaged models that do …

The bidomain model is considered to be the gold standard for numerical simulation of the
electrophysiology of cardiac tissue. The model provides important insights into the …

Cardiomyocyte calcium-handling is the key mediator of cardiac excitation-contraction
coupling. In the healthy heart, calcium controls both electrical impulse propagation and …

The atrioventricular node (AVN) is a crucial component of the cardiac conduction system.
Despite its pivotal role in regulating the transmission of electrical signals between atria and …

Chloroquine and hydroxychloroquine have been proposed recently as therapy for SARS-
CoV-2-infected patients, but during 3 months of extensive use concerns were raised related …

The goal of this mini-review is to summarize the collective experience of the authors for how
modeling and simulation approaches have been used to inform various decision points from …

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia, affecting more than 33
million people worldwide. Despite important advances in therapy, AF's incidence remains …

This work aims at proposing a fast time integral (FTI) method for the space-time fractional
Fitzhugh-Nagumo (FHN) monodomain model in irregular domains, which is commonly used …