Recent developments in the synthesis of biologically relevant selenium-containing scaffolds

B Banerjee, M Koketsu - Coordination Chemistry Reviews, 2017 - Elsevier
Recent, many methods have been reported for the synthesis of selenium-containing
bioactive scaffolds because of their interesting reactivity and potential pharmaceutical …

A review on recent synthetic strategies and pharmacological importance of 1, 3-thiazole derivatives

S Nayak, SL Gaonkar - Mini reviews in medicinal chemistry, 2019 - ingentaconnect.com
Thiazole is the most common heterocyclic compound in heterocyclic chemistry and in drug
design. Presence of several reaction sites in the thiazole moiety extends their range of …

Design, synthesis and biological screening of new 4-thiazolidinone derivatives with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile

KRA Abdellatif, MA Abdelgawad, HAH Elshemy… - Bioorganic …, 2016 - Elsevier
Two series of new thiazolidin-4-one derivatives 4a–c and 8a–e were designed and
prepared. All the synthesized compounds were evaluated for their in vitro COX-2 selectivity …

Synthesis and potential antimicrobial activity of novel α-aminophosphonates derivatives bearing substituted quinoline or quinolone and thiazole moieties

B Litim, A Djahoudi, S Meliani, A Boukhari - Medicinal Chemistry …, 2022 - Springer
To develop novel antimicrobial agents, and based on the biologically active heterocyclic
quinoline and thiazole substituted, a series of novel α-aminophosphonates (9a–h) and (10i …

Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies

MF Abo-Ashour, WM Eldehna, A Nocentini… - Bioorganic …, 2019 - Elsevier
In the presented work, we report the design and synthesis of novel SLC-0111 thiazole and
thiadiazole analogues (11a–d, 12a–d, 16a–c and 17a–d). A bioisosteric replacement …

Synthesis, in‐vitro and in‐silico study of novel thiazoles as potent antibacterial agents and MurB inhibitors

SMH Sanad, AAM Ahmed, AEM Mekky - Archiv der Pharmazie, 2020 - Wiley Online Library
Efficient procedures are herein reported for the synthesis of novel hybrid thiazoles via a one‐
pot three‐component protocol. The protocol involves the reaction of novel aldehyde …

Synthetic and medicinal perspective of fused-thiazoles as anticancer agents

S Pawar, K Kumar, MK Gupta… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Background: Cancer is second leading disease after cardiovascular disease. Presently,
Chemotherapy, Radiotherapy and use of chemicals are some treatments available these …

Visible light triggered, catalyst free approach for the synthesis of thiazoles and imidazo [2, 1-b] thiazoles in EtOH: H 2 O green medium

A Mishra, M Srivastava, P Rai, S Yadav, BP Tripathi… - RSC …, 2016 - pubs.rsc.org
The development of a visible light promoted, mild and greener approach for the synthesis of
highly functionalized thiazoles and imidazo [2, 1-b] thiazoles under photochemical activation …

Novel Thiazolidine-2, 4-dione-trimethoxybenzene-thiazole Hybrids as Human Topoisomerases Inhibitors

MS Sinicropi, J Ceramella, P Vanelle, D Iacopetta… - Pharmaceuticals, 2023 - mdpi.com
Cancer is a complex and heterogeneous disease and is still one of the leading causes of
morbidity and mortality worldwide, mostly as the population ages. Despite the encouraging …

[PDF][PDF] Recent Developments and Biological Activities of 2-Aminothiazole Derivatives.

ME Khalifa - Acta Chimica Slovenica, 2018 - researchgate.net
Aminothiazole nuclei and their various derivatives have been long used as precursors for
the synthesis of biologically active molecules. As a typical heterocyclic amine, 2 …