Immunobiology of atherosclerosis: a complex net of interactions

B Herrero-Fernandez, R Gomez-Bris… - International Journal of …, 2019 - mdpi.com
Cardiovascular disease is the leading cause of mortality worldwide, and atherosclerosis the
principal factor underlying cardiovascular events. Atherosclerosis is a chronic inflammatory …

Antigen-presenting dendritic cells in atherosclerosis

J Gil-Pulido, A Zernecke - European journal of pharmacology, 2017 - Elsevier
Atherosclerosis is characterized by lipid accumulation and chronic inflammation of the
arterial wall, involving both innate and adaptive immune responses. Accumulation of lipid …

The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells

AS Yousif, L Ronsard, P Shah, T Omatsu… - Immunity, 2021 - cell.com
Summary The interleukin-6 (IL-6) membrane receptor and its circulating soluble form, sIL-
6R, can be targeted by antibody therapy to reduce deleterious immune signaling caused by …

Dendritic cells and T cells, partners in atherogenesis and the translating road ahead

L Sun, W Zhang, Y Zhao, F Wang, S Liu, L Liu… - Frontiers in …, 2020 - frontiersin.org
Atherosclerosis is a chronic process associated with arterial inflammation, the accumulation
of lipids, plaque formation in vessel walls, and thrombosis with late mortal complications …

Macrophage-Associated Lipin-1 Enzymatic Activity Contributes to Modified Low-Density Lipoprotein–Induced Proinflammatory Signaling and Atherosclerosis

AE Vozenilek, AR Navratil, JM Green… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Macrophage proinflammatory responses induced by modified low-density
lipoproteins (modLDL) contribute to atherosclerotic progression. How modLDL causes …

[HTML][HTML] In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T …

A Christ, SL Maas, H Jin, C Lu, B Legein… - Free Radical Biology …, 2024 - Elsevier
Background and aims Dendritic cells (DCs), professional antigen-presenting cells, play an
important role in pathologies by controlling adaptive immune responses. However, their …

[HTML][HTML] Postnatal depletion of maternal cells biases T lymphocytes and natural killer cells' profiles toward early activation in the spleen

FS Castellan, N Irie - Biology Open, 2022 - journals.biologists.com
The maternal cells transferred into the fetus during gestation persist long after birth in the
progeny. These maternal cells have been hypothesized to promote the maturation of the …

hMRP8-ATTAC Mice: A New Model for Conditional and Reversible Neutrophil Ablation

DEM Duits, C Salvagno, EAM Raeven, K Vrijland… - Cells, 2022 - mdpi.com
Neutrophils are not only crucial immune cells for the neutralization of pathogens during
infections, but they are also key players in tissue repair and cancer. Several methods are …

Long-term sustainable dendritic cell-specific depletion murine model for periodontitis research

AF Stadler, M Patel, R Pacholczyk, CW Cutler… - Journal of …, 2017 - Elsevier
Dendritic cells (DCs) are specialized antigen-presenting cells that play a pivotal role in the
pathogenesis of periodontitis. The use of animal models to study the role of DCs in …

[PDF][PDF] Bedeutung Clec9a-abhängiger Immunzellen in kardialen Entzündungsprozessen

D Messerer - 2020 - edoc.ub.uni-muenchen.de
Der Myokardinfarkt ist die am meisten verbreitete und klinisch relevanteste Form der akuten
Herzerkrankungen. Hierbei kommt es als Folge einer Ischämie zum abrupten Absterben von …