Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines

N Fattahi, MA Shahbazi, A Maleki, M Hamidi… - Journal of Controlled …, 2020 - Elsevier
Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …

[HTML][HTML] High variability of genomic instability and gene expression profiling in different HeLa clones

A Frattini, M Fabbri, R Valli, E De Paoli… - Scientific reports, 2015 - nature.com
The HeLa cell line is one of the most popular cell lines in biomedical research, despite its
well-known chromosomal instability. We compared the genomic and transcriptomic profiles …

Synthesis, structures, molecular docking, cytotoxicity and bioimaging studies of two novel Zn (II) complexes

E Gao, N Sun, S Zhang, Y Ding, X Qiu, Y Zhan… - European Journal of …, 2016 - Elsevier
Abstract Two novel compounds [Zn 2 (Endc) 2 (bipy) 2 (H 2 O) 3]· 4 (H 2 O)· 2 (O)(1),[Zn 2
(Endc) 2 (phen) 2 (H 2 O)]·(O)(2)(bipy= 2, 2-bipyridine, phen= 1, 10-phenanthroline, and …

Unravelling the metabolomic diversity of pigmented and non-pigmented traditional rice from Tamil Nadu, India

V Subramanian, UN Dhandayuthapani, S Kandasamy… - BMC Plant …, 2024 - Springer
Rice metabolomics is widely used for biomarker research in the fields of pharmacology. As a
consequence, characterization of the variations of the pigmented and non-pigmented …

Pro-apoptotic activity of nano-escheriosome based oleic acid conjugate against 7, 12-dimethylbenz (a) anthracene (DMBA) induced cutaneous carcinogenesis

AA Khan - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Abstract Aim 2, 6-Diisopropylphenol-oleic acid (2, 6P-OLA) is an ester conjugate of oleic
acid that has displayed a strong anticancer activity on different types of cancer cell lines …

优质食味粳稻辽粳433 和越光糙米代谢产物差异分析

沈枫, 蒋洪波, 刘博, 张秀茹, 刘军, 解文孝, 姚继攀… - 中国水稻科学, 2020 - ricesci.cn
[目的] 分析优质食味粳稻辽粳433 和越光之间代谢产物差异, 为优质食味粳稻辽粳433
推广及优质食味粳稻品种选育提供参考.[方法] 利用气相色谱-质谱(GC-MS) 检测辽粳433 …

Difference of metabolites in brown rice between Liaojing 433 and Koshihikari with good eating quality

S Feng, H JIANG, LIU Bo, X ZHANG, LIU Jun… - Chinese Journal OF …, 2020 - ricesci.cn
[Objective] Our goal is to analyze the metabolite difference between good eating-quality
japonica rice Liaojing 433 and Koshihikari, and provide reference for breeding good eating …

Biophysical interactions, docking studies and cytotoxic potential of a novel propofol-linolenate: a multi-technique approach

AM Alanazi, AA Khan, MT Rehman… - Journal of …, 2020 - Taylor & Francis
In the present study, we have analyzed the biophysical interactions of alpha-linolenic acid
conjugate (2, 6P-ALA) with human serum albumin (HSA) and calf thymus DNA (CT-DNA); …