The current treatment strategies for diabetic wound care provide only moderate degree of
effectiveness; hence new and improved therapeutic techniques are in great demand …

It is well‏‏ established that macrophages are key regulators of wound healing, displaying
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …

Macrophages are key immune cells that respond to infections, and modulate
pathophysiological conditions such as wound healing. By possessing phagocytic activities …

Non-healing, chronic wounds place a huge burden on healthcare systems as well as
individual patients. These chronic wounds especially diabetic wounds will ultimately lead to …

Wounds are an excellent example of how the field of dermatology represents a cross-section
of many medical disciplines. For instance, wounds may be caused by trauma, vascular …

Diabetes mellitus (DM) is a common endocrine disease characterized by a state of
hyperglycemia (higher level of glucose in the blood than usual). DM and its complications …

Wound healing is the physiologic response to tissue trauma proceeding as a complex
pathway of biochemical reactions and cellular events, secreted growth factors, and …

Chronic wounds represent a major public health issue, with an extremely high cost
worldwide. In healthy individuals, the wound healing process takes place in different stages …

Given their severity and non-healing nature, diabetic chronic wounds are a significant
concern to the 30.3 million Americans diagnosed with diabetes mellitus (2015). Peripheral …

Macrophages are mononuclear phagocytes established during embryogenesis and derived
from the yolk sac or the fetal liver but also recruited from the blood and bone marrow under …