Next-generation sequencing: insights to advance clinical investigations of the microbiome

CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …

Dietary fibre modulates the gut microbiota

P Cronin, SA Joyce, PW O'Toole, EM O'Connor - Nutrients, 2021 - mdpi.com
Dietary fibre has long been established as a nutritionally important, health-promoting food
ingredient. Modern dietary practices have seen a significant reduction in fibre consumption …

[HTML][HTML] High-fat diet promotes colorectal tumorigenesis through modulating gut microbiota and metabolites

J Yang, H Wei, Y Zhou, CH Szeto, C Li, Y Lin… - Gastroenterology, 2022 - Elsevier
Background and Aims Dietary fat intake is associated with increased risk of colorectal
cancer (CRC). We examined the role of high-fat diet (HFD) in driving CRC through …

[HTML][HTML] Gut-microbiota-targeted diets modulate human immune status

HC Wastyk, GK Fragiadakis, D Perelman, D Dahan… - Cell, 2021 - cell.com
Diet modulates the gut microbiome, which in turn can impact the immune system. Here, we
determined how two microbiota-targeted dietary interventions, plant-based fiber and …

The intestinal microbiota and colorectal cancer

Y Cheng, Z Ling, L Li - Frontiers in immunology, 2020 - frontiersin.org
The intestinal microbiota, composed of a large population of microorganisms, is often
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …

[HTML][HTML] Rethinking healthy eating in light of the gut microbiome

AM Armet, EC Deehan, AF O'Sullivan, JF Mota… - Cell Host & Microbe, 2022 - cell.com
Given the worldwide epidemic of diet-related chronic diseases, evidence-based dietary
recommendations are fundamentally important for health promotion. Despite the importance …

[HTML][HTML] Plant-derived bioactive compounds in colon cancer treatment: An updated review

A Esmeeta, S Adhikary, V Dharshnaa… - Biomedicine & …, 2022 - Elsevier
Colon cancer is the third most predominant cancer caused by genetic, environmental and
nutritional factors. Plant-based compounds are very well known to regress colon cancer in …

American Cancer Society guideline for diet and physical activity for cancer prevention

CL Rock, C Thomson, T Gansler… - CA: a cancer journal …, 2020 - Wiley Online Library
Abstract The American Cancer Society (ACS) publishes the Diet and Physical Activity
Guideline to serve as a foundation for its communication, policy, and community strategies …

Colorectal cancer statistics, 2023

RL Siegel, NS Wagle, A Cercek… - CA: a cancer journal …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is the second most common cause of cancer death in the United
States. Every 3 years, the American Cancer Society provides an update of CRC statistics …

Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

NN Keum, E Giovannucci - Nature reviews Gastroenterology & …, 2019 - nature.com
Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the
second leading cause of cancer death. Arising through three major pathways, including …