Metabolic hormones are integral regulators of female reproductive health and function

F Athar, M Karmani, NM Templeman - Bioscience Reports, 2024 - portlandpress.com
The female reproductive system is strongly influenced by nutrition and energy balance. It is
well known that food restriction or energy depletion can induce suppression of reproductive …

Increase of serum lipoprotein (a), an adverse effect of growth hormone treatment

Z Laron - Growth Hormone & IGF Research, 2022 - Elsevier
A number of reports show that high endogenous, or therapeutic administration of human
growth hormone (hGH) cause an increase of serum lipoprotein a, Lp (a). Being …

Safety and efficacy of lonapegsomatropin in children with growth hormone deficiency: enliGHten trial 2-year results

AK Maniatis, SJ Casella, UM Nadgir… - The Journal of …, 2022 - academic.oup.com
Purpose The objectives of the ongoing, Phase 3, open-label extension trial enliGHten are to
assess the long-term safety and efficacy of weekly administered long-acting growth hormone …

Safety and Effectiveness of a Biosimilar Recombinant Human Growth Hormone in Children Requiring Growth Hormone Treatment: Analysis of Final Data from PATRO …

S Loche, S Kanumakala, P Backeljauw… - Drug design …, 2024 - Taylor & Francis
Purpose Omnitrope®(somatropin) was approved as a biosimilar recombinant human growth
hormone (rhGH) in 2006. Here, we report final data from the PAtients TReated with …

Occupation, Literacy, Anthropometric Traits, and Life Expectancy of Italian Men Born 1900–1910: Evidence From Military Conscription Registers

F Bruno, MA Aceto, P Abondio… - Journal of Aging …, 2023 - journals.sagepub.com
Objective The aim is to explore the role of anthropometric traits and sociodemographic
characteristics on human survival. Methods Anthropometrics and sociodemographic data of …

Childhood growth hormone treatment: challenges, opportunities, and considerations

A Tidblad, L Sävendahl - The Lancet Child & Adolescent Health, 2024 - thelancet.com
With long standing demand and popularity, growth hormone treatments continue to be a
topic of interest for paediatric endocrinologists and general paediatricians due to ongoing …

Association between recombinant growth hormone therapy and all-cause mortality and cancer risk in childhood: systematic review and meta-analysis

M He, X Deng, X Wang, Y Wan, J Huang… - Frontiers in …, 2022 - frontiersin.org
Objectives The safety of recombinant human growth hormone (rhGH) treatment in childhood
and the role of rhGH therapy in promoting tumorigenesis and progression have been the …

Administration of insulin like growth factor I (IGFI) lowers serum lipoprotein (a)-impact on atherosclerotic cardiovascular disease

Z Laron, H Werner - Growth Hormone & IGF Research, 2023 - Elsevier
Insulin like growth factor I (IGFsingle bondI) secreted by the liver upon stimulation by
pituitary growth hormone (GH) acts as the most important growth stimulating hormone in …

[HTML][HTML] Involvement of α-klotho in growth hormone (GH) signaling

M Koike, T Sato, Y Shiozaki, A Komiya… - Journal of Clinical …, 2024 - ncbi.nlm.nih.gov
Growth hormone (GH) exerts multiple effects on different organs directly or via its main
mediator, insulin-like growth factor1 (IGF1). In this study, we focused on the novel …

Effects of growth hormone therapy on the onset and progression of pubertal development in girls with idiopathic short stature

F Zhu, Q Xu, L Huang, J Zhu, L Huang… - Gynecological …, 2024 - Taylor & Francis
Objective The aim of this study was to explore the impact of growth hormone (GH) therapy
on the onset and progression of puberty in girls with idiopathic short stature. Methods This …