The roles and mechanisms of lncRNAs in liver fibrosis

Z He, D Yang, X Fan, M Zhang, Y Li, X Gu… - International journal of …, 2020 - mdpi.com
Many studies have revealed that circulating long noncoding RNAs (lncRNAs) regulate gene
and protein expression in the process of hepatic fibrosis. Liver fibrosis is a reversible wound …

Hepatocellular carcinoma mechanisms associated with chronic HCV infection and the impact of direct-acting antiviral treatment

S Dash, Y Aydin, KE Widmer… - Journal of hepatocellular …, 2020 - Taylor & Francis
Hepatitis C virus (HCV) infection is the major risk factor for liver cirrhosis and hepatocellular
carcinoma (HCC). The mechanisms of HCC initiation, growth, and metastasis appear to be …

[HTML][HTML] Efficacy and safety of anti-hepatic fibrosis drugs

K Damiris, ZH Tafesh, N Pyrsopoulos - World Journal of …, 2020 - ncbi.nlm.nih.gov
Recent progress in our understanding of the pathways linked to progression from hepatic
insult to cirrhosis has led to numerous novel therapies being investigated as potential cures …

Regression of liver fibrosis and hepatocellular carcinoma development after HCV eradication with oral antiviral agents

HW Yoo, JY Park, SG Kim, YK Jung, SH Lee, MY Kim… - Scientific reports, 2022 - nature.com
We prospectively investigated the changes of liver stiffness (LS) and the occurrence of
hepatocellular carcinoma (HCC) after hepatitis C virus (HCV) eradication using direct …

Liver function following hepatitis C virus eradication by direct acting antivirals in patients with liver cirrhosis: data from the PITER cohort

MG Quaranta, L Ferrigno, X Tata, F D'Angelo… - BMC infectious …, 2021 - Springer
Background The development of direct-acting antivirals (DAA) for HCV has revolutionized
the treatment of HCV, including its treatment in patients with HIV coinfection. The aim of this …

HCV cure with direct-acting antivirals improves liver and immunological markers in HIV/HCV-coinfected patients

Ó Brochado-Kith, I Martínez, J Berenguer… - Frontiers in …, 2021 - frontiersin.org
Hepatitis C virus (HCV) cure after all-oral direct-acting antiviral (DAA) therapy greatly
improves the liver and immune system. We aimed to assess the impact of this HCV …

Role of hepatitis c virus in hepatocellular carcinoma and neurological disorders: an overview

M Suhail, SS Sohrab, MA Kamal, EI Azhar - Frontiers in Oncology, 2022 - frontiersin.org
The hepatitis C virus (HCV) causes serious issues, affecting 71 million people globally. The
most common manifestations range from chronic hepatitis to liver cirrhosis, leading to …

Incidence, prevalence and risk factors for hepatitis C in Danish prisons

J Søholm, DK Holm, B Mössner, LW Madsen… - PloS one, 2019 - journals.plos.org
Hepatitis C virus (HCV) infection is prevalent among people in prison and prisons could
therefore represent a unique opportunity to test risk groups for HCV. The aim of this sero …

Role of long non‑coding RNAs and related epigenetic mechanisms in liver fibrosis

N Ganguly, S Chakrabarti - … Journal of Molecular …, 2021 - spandidos-publications.com
Liver fibrosis is one of the major liver pathologies affecting patients worldwide. It results from
an improper tissue repair process following liver injury or inflammation. If left untreated, it …

[HTML][HTML] Fibrosis regression following hepatitis C antiviral therapy

A Elsharkawy, R Samir, M El-Kassas - World Journal of Hepatology, 2022 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection is one of the most common causes of liver pathology. It is a
major etiological factor of continuous liver injury by triggering an uncontrolled inflammatory …