Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

Glucocorticoids are widely used to suppress inflammation or the immune system. High
doses and long-term use of glucocorticoids lead to an important and common iatrogenic …

Background Triple fixed-dose regimens of an inhaled glucocorticoid, a long-acting
muscarinic antagonist (LAMA), and a long-acting β2-agonist (LABA) for chronic obstructive …

In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

This Executive Summary of the Global Strategy for the Diagnosis, Management, and
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …

Osteoporosis or porous bone disorder is the result of an imbalance in an otherwise highly
balanced physiological process known as 'bone remodeling'. The immune system is …

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer …

Background Researchers and organizations often use evidence from randomized controlled
trials (RCTs) to determine the efficacy of a treatment or intervention under ideal conditions …

The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

Comorbidities are frequent in chronic obstructive pulmonary disease (COPD) and
significantly impact on patients' quality of life, exacerbation frequency, and survival. There is …