Polyene natural products
C Thirsk, A Whiting - Journal of the Chemical Society, Perkin …, 2002 - pubs.rsc.org
Polyene natural products - Journal of the Chemical Society, Perkin Transactions 1 (RSC
Publishing) DOI:10.1039/B109741P Royal Society of Chemistry View PDF VersionPrevious …
Publishing) DOI:10.1039/B109741P Royal Society of Chemistry View PDF VersionPrevious …
Acylvinyl and vinylogous synthons
R Chinchilla, C Nájera - Chemical Reviews, 2000 - ACS Publications
The functionality-(CHdCH) nCO-is an important structural feature in many naturally occurring
compounds such as oxopolyenoic acids, lactones, and polyenamides. 1 Consequently …
compounds such as oxopolyenoic acids, lactones, and polyenamides. 1 Consequently …
Efficient microwave-assisted Suzuki–Miyaura cross-coupling reaction of 3-bromo pyrazolo [1, 5-a] pyrimidin-5 (4 H)-one: Towards a new access to 3, 5-diarylated 7 …
A convenient and efficient synthetic route to C3-arylated 7-trifluoromethylpyrazolo [1, 5-a]
pyrimidin-5-one derivatives has been reported starting from 3-bromo-7-(trifluoromethyl) …
pyrimidin-5-one derivatives has been reported starting from 3-bromo-7-(trifluoromethyl) …
Stereospecific approach to α, β-disubstituted nitroalkenes via coupling of α-bromonitroalkenes with boronic acids and terminal acetylenes
M Ganesh, INN Namboothiri - Tetrahedron, 2007 - Elsevier
(Z)-α-Bromo-β-substituted nitroethylenes undergo facile Suzuki coupling with aryl,
heteroaryl, and vinylboronic acids in the presence of Pd (PPh3) 4 as catalyst to afford (E)-α …
heteroaryl, and vinylboronic acids in the presence of Pd (PPh3) 4 as catalyst to afford (E)-α …
Approach toward the Total Synthesis of Orevactaene. 2. Convergent and Stereoselective Synthesis of the C18− C31 Domain of Orevactaene. Evidence for the …
MG Organ, YV Bilokin, S Bratovanov - The Journal of Organic …, 2002 - ACS Publications
The synthesis of the C18− C31 subunit of orevactaene (1) in an enantioselective and
convergent manner is reported. Four chiral centers in the structure (ie, carbons 23, 25, 32 …
convergent manner is reported. Four chiral centers in the structure (ie, carbons 23, 25, 32 …
Cross‐Coupling Reactions of Organosilicon Compounds in the Stereocontrolled Synthesis of Retinoids
J Bergueiro, J Montenegro, F Cambeiro… - … A European Journal, 2012 - Wiley Online Library
This paper presents a full account of the use of Hiyama cross‐coupling reactions in a highly
convergent approach to retinoids in which the key step is construction of the central C10 …
convergent approach to retinoids in which the key step is construction of the central C10 …
Hiyama cross-coupling reaction in the stereospecific synthesis of retinoids
The first application of the Hiyama reaction to the synthesis of retinoids is reported. A range
of organosilicon moieties (siloxanes, silanols and three kinds of “safety-catch” silanols) were …
of organosilicon moieties (siloxanes, silanols and three kinds of “safety-catch” silanols) were …
A comprehensive survey of stille-type Csp2-Csp2 single bond forming processes in the synthesis of retinoic acid and analogs
B Domínguez, B Iglesias, AR de Lera - Tetrahedron, 1999 - Elsevier
The synthesis of the retinoid skeleton has been exhaustively explored using the Stille
coupling for the formation of the side-chain single bonds. On employing the experimental …
coupling for the formation of the side-chain single bonds. On employing the experimental …
Approach toward the total synthesis of orevactaene. Part 1: Assembly of the contiguous trisubstituted olefin component
MG Organ, S Bratovanov - Tetrahedron Letters, 2000 - Elsevier
An approach to the conjugated polyene chain component of orevactaene is reported. A
modular approach has been devised to link the two stereocentre-containing ends of the …
modular approach has been devised to link the two stereocentre-containing ends of the …
Highly regio-and stereoselective hydrometallation reactions of fluorine-containing internal alkynes: Novel approaches to fluoroalkylated alkenes
T Konno, J Chae, T Tanaka, T Ishihara… - Journal of fluorine …, 2006 - Elsevier
Hydroalumination, hydrocupration, and hydroboration reactions of various fluorine-
containing alkynes were investigated. The alkyne reacted smoothly with 2.0 equiv. of Red-Al …
containing alkynes were investigated. The alkyne reacted smoothly with 2.0 equiv. of Red-Al …