Picornaviruses
TJ Tuthill, E Groppelli, JM Hogle… - Cell Entry by Non …, 2010 - Springer
The picornavirus family consists of a large number of small RNA viruses, many of which are
significant pathogens of humans and livestock. They are amongst the simplest of vertebrate …
significant pathogens of humans and livestock. They are amongst the simplest of vertebrate …
Acid-dependent viral entry
Á Vázquez-Calvo, JC Saiz, KC McCullough, F Sobrino… - Virus research, 2012 - Elsevier
Virus infection of host cells requires that entry into the cell results in efficient genome release
leading to translation and replication. These initial steps revolving around the entry and …
leading to translation and replication. These initial steps revolving around the entry and …
Productive entry of foot-and-mouth disease virus via macropinocytosis independent of phosphatidylinositol 3-kinase
SC Han, HC Guo, SQ Sun, Y Jin, YQ Wei, X Feng… - Scientific reports, 2016 - nature.com
Virus entry is an attractive target for therapeutic intervention. Here, using a combination of
electron microscopy, immunofluorescence assay, siRNA interference, specific …
electron microscopy, immunofluorescence assay, siRNA interference, specific …
The pH stability of foot-and-mouth disease virus particles is modulated by residues located at the pentameric interface and in the N terminus of VP1
F Caridi, A Vázquez-Calvo, F Sobrino… - Journal of …, 2015 - Am Soc Microbiol
The picornavirus foot-and-mouth disease virus (FMDV) is the etiological agent of a highly
contagious disease that affects important livestock species. The FMDV capsid is highly acid …
contagious disease that affects important livestock species. The FMDV capsid is highly acid …
The Insufficient Activation of RIG-I–Like Signaling Pathway Contributes to Highly Efficient Replication of Porcine Picornaviruses in IBRS-2 Cells
X Zhang, F Yang, K Li, W Cao, Y Ru, S Chen… - Molecular & Cellular …, 2021 - ASBMB
Seneca Valley virus (SVV) or commonly known as senecavirus A, is one of the picornavirus
that is associated with vesicular disease and neonatal mortality in swine herds. Our previous …
that is associated with vesicular disease and neonatal mortality in swine herds. Our previous …
A single amino acid substitution in the capsid of foot-and-mouth disease virus can increase acid resistance
MA Martín-Acebes, A Vázquez-Calvo, V Rincón… - Journal of …, 2011 - Am Soc Microbiol
Foot-and-mouth disease virus (FMDV) particles lose infectivity due to their disassembly at
pH values slightly below neutrality. This acid-dependent disassembly process is required for …
pH values slightly below neutrality. This acid-dependent disassembly process is required for …
Foot-and-mouth disease virus particles inactivated with binary ethylenimine are efficiently internalized into cultured cells
MA Martín-Acebes, Á Vázquez-Calvo… - Vaccine, 2011 - Elsevier
Conventional foot-and-mouth disease (FMD) vaccines are produced from virus grown in cell
culture that is chemically inactivated by using binary ethylenimide (BEI). Here, we show that …
culture that is chemically inactivated by using binary ethylenimide (BEI). Here, we show that …
Plasma membrane phosphatidylinositol 4, 5 bisphosphate is required for internalization of foot-and-mouth disease virus and vesicular stomatitis virus
A Vazquez-Calvo, F Sobrino, MA Martín-Acebes - 2012 - journals.plos.org
Phosphatidylinositol-4, 5-bisphosphate, PI (4, 5) P2, is a phospholipid which plays important
roles in clathrin-mediated endocytosis. To investigate the possible role of this lipid on viral …
roles in clathrin-mediated endocytosis. To investigate the possible role of this lipid on viral …
Different functional sensitivity to mutation at intersubunit interfaces involved in consecutive stages of foot-and-mouth disease virus assembly
V Rincon, A Rodríguez-Huete… - Journal of General …, 2015 - microbiologyresearch.org
Small spherical viruses are paradigms of supramolecular self-assembly. Identifying the
specific structural determinants for virus assembly provides guidelines to develop new …
specific structural determinants for virus assembly provides guidelines to develop new …
Modulation of foot-and-mouth disease virus pH threshold for uncoating correlates with differential sensitivity to inhibition of cellular Rab GTPases and decreases …
A Vazquez-Calvo, F Caridi… - Journal of general …, 2012 - microbiologyresearch.org
The role of cellular Rab GTPases that govern traffic between different endosome
populations was analysed on foot-and-mouth disease virus (FMDV) infection. Changes of …
populations was analysed on foot-and-mouth disease virus (FMDV) infection. Changes of …