Main In recent years, substantial advances in social neuroscience have been realized,
including the generation of numerous rodent models of autism spectrum disorder. Still, it can …

In the past few years, several experimental studies have suggested that empathy occurs in
the social lives of rodents. Thus, rodent behavioral models can now be developed to …

Neurodevelopmental disorders, including autism spectrum disorder (ASD), are defined by
core behavioral impairments; however, subsets of individuals display a spectrum of …

Schizophrenia and autism are thought to result from the interaction between a susceptibility
genotype and environmental risk factors. The offspring of women who experience infection …

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

Three defining clinical symptoms of autism are aberrant reciprocal social interactions,
deficits in social communication, and repetitive behaviors, including motor stereotypies and …

To support the role of DISC1 in human psychiatric disorders, we identified and analyzed two
independently derived ENU-induced mutations in Exon 2 of mouse Disc1. Mice with …

BACKGROUND: Gene-environment interactions (GEI) are involved in the pathogenesis of
mental diseases. We evaluated interaction between mutant human disrupted-in …

Neurodevelopmental disorders such as autism and fragile X syndrome were long thought to
be medically untreatable, on the assumption that brain dysfunctions were immutably …

Social approach is crucial for establishing relationships among individuals. In rodents, social
approach has been studied primarily within the context of behavioral phenomena related to …