Clostridium difficile infection (CDI) has significant clinical impact especially on the elderly
and/or immunocompromised patients. The pathogenicity of Clostridium difficile is mainly …

Foreword This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a review of …

Since publication of the Society for Healthcare Epidemiology of America position paper on
Clostridium difficile infection in 1995, significant changes have occurred in the epidemiology …

As the leading cause of hospital-acquired diarrhea, Clostridium difficile colonizes the large
bowel of patients undergoing antibiotic therapy and produces two toxins, which cause …

Clostridium difficile is the leading cause of infectious diarrhoea in hospitals worldwide,
because of its virulence, spore-forming ability and persistence,. C. difficile-associated …

Objective: To update the practice parameters for the evaluation of adult patients who
develop a new fever in the intensive care unit, for the purpose of guiding clinical practice …

Prompt and precise diagnosis is an important aspect of effective management of Clostridium
difficile infection (CDI). CDI causes 15%–25% of all cases of antibiotic-associated diarrhea …

BACKGROUND & AIMS: Infection with Clostridium difficile causes nosocomial antibiotic–
associated diarrhea and colitis. Hamsters historically have been used to investigate disease …

US hospital discharges for which Clostridium difficile–associated disease (CDAD) was listed
as any diagnosis doubled from 82,000 (95% confidence interval [CI] 71,000–94,000) or …

Rates and severity of Clostridium difficile infection (CDI) in hospitals in North America and
Europe have increased since 2000 and correlate with dissemination of an epidemic strain …