BAFF and BAFF-receptor in B cell selection and survival

CR Smulski, H Eibel - Frontiers in immunology, 2018 - frontiersin.org
The BAFF-receptor (BAFFR) is encoded by the TNFRSF13C gene and is one of the main pro-
survival receptors in B cells. Its function is impressively documented in humans by a …

Phagocytosis: receptors, signal integration, and the cytoskeleton

SA Freeman, S Grinstein - Immunological reviews, 2014 - Wiley Online Library
Phagocytosis is a remarkably complex and versatile process: it contributes to innate
immunity through the ingestion and elimination of pathogens, while also being central to …

Membrane phase separation drives responsive assembly of receptor signaling domains

SA Shelby, I Castello-Serrano, KC Wisser… - Nature Chemical …, 2023 - nature.com
Plasma membrane heterogeneity has been tied to a litany of cellular functions and is often
explained by analogy to membrane phase separation; however, models based on phase …

CD81 controls beige fat progenitor cell growth and energy balance via FAK signaling

Y Oguri, K Shinoda, H Kim, DL Alba, WR Bolus… - Cell, 2020 - cell.com
Adipose tissues dynamically remodel their cellular composition in response to external cues
by stimulating beige adipocyte biogenesis; however, the developmental origin and …

Beyond antigens and adjuvants: formulating future vaccines

TJ Moyer, AC Zmolek, DJ Irvine - The Journal of clinical …, 2016 - Am Soc Clin Investig
The need to optimize vaccine potency while minimizing toxicity in healthy recipients has
motivated studies of the formulation of vaccines to control how, when, and where antigens …

The life cycle of phagosomes: formation, maturation, and resolution

R Levin, S Grinstein, J Canton - Immunological reviews, 2016 - Wiley Online Library
Phagocytosis, the regulated uptake of large particles (> 0.5 μm in diameter), is essential for
tissue homeostasis and is also an early, critical component of the innate immune response …

The 2015 super-resolution microscopy roadmap

SW Hell, SJ Sahl, M Bates, X Zhuang… - Journal of Physics D …, 2015 - iopscience.iop.org
Far-field optical microscopy using focused light is an important tool in a number of scientific
disciplines including chemical,(bio) physical and biomedical research, particularly with …

Tetraspanins at a glance

S Charrin, S Jouannet, C Boucheix… - Journal of cell …, 2014 - journals.biologists.com
Tetraspanins are a family of proteins with four transmembrane domains that play a role in
many aspects of cell biology and physiology; they are also used by several pathogens for …

Tetraspanins: structure, dynamics, and principles of partner-protein recognition

KJ Susa, AC Kruse, SC Blacklow - Trends in cell biology, 2024 - cell.com
Tetraspanins are a large, highly conserved family of four-pass transmembrane (TM) proteins
that play critical roles in a variety of essential cellular functions, including cell migration …

Crystal structure of a full-length human tetraspanin reveals a cholesterol-binding pocket

B Zimmerman, B Kelly, BJ McMillan, TCM Seegar… - Cell, 2016 - cell.com
Tetraspanins comprise a diverse family of four-pass transmembrane proteins that play
critical roles in the immune, reproductive, genitourinary, and auditory systems. Despite their …