Circulating tumor cells: from new biological insights to clinical practice

X Gu, S Wei, X Lv - Signal Transduction and Targeted Therapy, 2024 - nature.com
The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Cell-free DNA: hope and potential application in cancer

Y Yan, Q Guo, F Wang, R Adhikari, Z Zhu… - Frontiers in cell and …, 2021 - frontiersin.org
Cell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as
biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA …

Circulating cell-free DNA in breast cancer: size profiling, levels, and methylation patterns lead to prognostic and predictive classifiers

M Panagopoulou, M Karaglani, I Balgkouranidou… - Oncogene, 2019 - nature.com
Blood circulating cell-free DNA (ccfDNA) is a suggested biosource of valuable clinical
information for cancer, meeting the need for a minimally-invasive advancement in the route …

Circulating cell-free DNA and colorectal cancer: a systematic review

V Vymetalkova, K Cervena, L Bartu… - International journal of …, 2018 - mdpi.com
There is a strong demand for the identification of new biomarkers in colorectal cancer (CRC)
diagnosis. Among all liquid biopsy analysts, cell-free circulating DNA (cfDNA) is probably …

[HTML][HTML] Blood-based DNA methylation signatures in cancer: A systematic review

Y Li, Z Fan, Y Meng, S Liu, H Zhan - … Acta (BBA)-Molecular Basis of Disease, 2023 - Elsevier
DNA methylation profiles are in dynamic equilibrium via the initiation of methylation,
maintenance of methylation and demethylation, which control gene expression and …

[HTML][HTML] Circulating tumour DNA (ctDNA) as a liquid biopsy for melanoma

L Calapre, L Warburton, M Millward, M Ziman, ES Gray - Cancer letters, 2017 - Elsevier
Circulating tumour DNA (ctDNA) has emerged as a promising blood-based biomarker for
monitoring disease status of patients with advanced cancers. In melanoma, ctDNA has been …

Diagnostic and prognostic role of cell‐free DNA testing for colorectal cancer patients

C Bedin, MV Enzo, P Del Bianco… - … journal of cancer, 2017 - Wiley Online Library
Circulating cell‐free DNA (cfDNA) was found in increased amounts in cancer patients and
tumor‐associated molecular alteration can be detected in cancer patient's samples. For this …

Colon cancer transcriptome

K Mokhtari, M Peymani, M Rashidi… - Progress in biophysics …, 2023 - Elsevier
Over the last four decades, methodological innovations have continuously changed
transcriptome profiling. It is now feasible to sequence and quantify the transcriptional outputs …

Cell-free circulating (tumor) DNA before surgery as a prognostic factor in non-metastatic colorectal cancer: a systematic review

SJ Schraa, KL van Rooijen, M Koopman, GR Vink… - Cancers, 2022 - mdpi.com
Simple Summary Patients with colorectal cancer without distant metastases are often cured
by surgical tumor resection. Follow-up is needed because of the risk of disease recurrence …

Prognostic value of circulating tumor DNA in patients with colon cancer: Systematic review

G Fan, K Zhang, X Yang, J Ding, Z Wang, J Li - PloS one, 2017 - journals.plos.org
The application of circulating tumor DNA (ctDNA) represents a non-invasive method for
tumor detection. Its prognostic significance in patients with colorectal cancer is controversial …