Tranexamic acid for the prevention and treatment of bleeding in surgery, trauma and bleeding disorders: a narrative review

A Ockerman, T Vanassche, M Garip, C Vandenbriele… - Thrombosis …, 2021 - Springer
Objectives We review the evidence for tranexamic acid (TXA) for the treatment and
prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight …

Understanding melasma-how can pharmacology and cosmetology procedures and prevention help to achieve optimal treatment results? A narrative review

Z Piętowska, D Nowicka, JC Szepietowski - International Journal of …, 2022 - mdpi.com
Melasma is a chronic skin condition that involves the overproduction of melanin in areas
exposed to ultraviolet radiation. Melasma treatment is long-term and complicated with …

Update on Melasma—part II: treatment

DP Cassiano, ACC Espósito, CN da Silva… - Dermatology and …, 2022 - Springer
Melasma is a prevalent chronic relapsing pigmentary disorder that affects photoexposed
areas, especially in women of childbearing age. Although there is currently no curative …

Tranexamic acid in melasma: A focused review on drug administration routes

H Konisky, E Balazic, JA Jaller… - Journal of cosmetic …, 2023 - Wiley Online Library
Background Melasma is a disorder of hyperpigmentation and vascularization often found in
women between the ages of 20 and 40. The pathogenesis is unknown, but melasma often …

Self‐applied topical interventions for melasma: a systematic review and meta‐analysis of data from randomized, investigator‐blinded clinical trials

A Pennitz, M Kinberger, G Avila Valle… - British Journal of …, 2022 - academic.oup.com
Background Melasma is a common dermatological condition. Although its relevance as a
skin condition is primarily of a cosmetic nature, it may affect the patient's wellbeing and …

Topical and systemic therapies in Melasma: a systematic review

R Sarkar, EB Handog, A Das, A Bansal… - Indian Dermatology …, 2023 - journals.lww.com
Materials and Methods: A systematic search was performed for all topical and systemic
treatments for melasma up till May 4, 2021, using the PubMed and EMBASE databases …

Perspectives of topical formulations for melasma

ACP de Freitas, RB Rigon, E Bagatin… - International Journal …, 2023 - Wiley Online Library
Melasma is acquired hyperpigmentation that mainly affects the face, can cause negative
changes in self‐esteem, and mostly affects women. Treatment is difficult, and different drugs …

Efficacy and tolerability of chemical peeling as a single agent for melasma in dark‐skinned patients: A systematic review and meta‐analysis of comparative trials

NA Dorgham, RA Hegazy, AK Sharobim… - Journal of Cosmetic …, 2020 - Wiley Online Library
Background Chemical peelings are used on a wide scale in cosmetic field including
melasma treatment. They often provide clinicians with flexibility in tailoring treatments …

Hyaluronic acid dissolving microneedle patch loaded with tranexamic acid for melasma treatment

C Zhang, X Song, C Ma, M Wang, H Deng… - International Journal of …, 2024 - Elsevier
Melasma is an acquired hypermelanotic condition characterized by the presence of irregular
light-to-dark brown macules that primarily manifest on the sun-exposed areas of the skin …

Liposomal azelaic acid 20% cream vs hydroquinone 4% cream as adjuvant to oral tranexamic acid in melasma: a comparative study

EM Akl - Journal of Dermatological Treatment, 2022 - Taylor & Francis
Background Melasma negatively impacts patient's quality of life (QoL). Although
hydroquinone 4% is the most prescribed treatment, several side effects had been reported …