Photoisomerization in different classes of azobenzene

HMD Bandara, SC Burdette - Chemical Society Reviews, 2012 - pubs.rsc.org
Azobenzene undergoes trans→ cisisomerization when irradiated with light tuned to an
appropriate wavelength. The reverse cis→ transisomerization can be driven by light or …

Azobenzene photoswitches for biomolecules

AA Beharry, GA Woolley - Chemical Society Reviews, 2011 - pubs.rsc.org
The photoisomerization of azobenzene has been known for almost 75 years but only
recently has this process been widely applied to biological systems. The central challenge of …

A molecular anion pump

B Shao, H Fu, I Aprahamian - Science, 2024 - science.org
Pumping ions against a concentration gradient through protein-based transporters is a
cornerstone of numerous biological processes. Mimicking this function by using artificial …

Chemical solutions for the closed-cycle storage of solar energy

TJ Kucharski, Y Tian, S Akbulatov… - Energy & Environmental …, 2011 - pubs.rsc.org
This review analyzes the inherent scientific challenges of realizing the potential of storing
solar energy by photochemical generation of high-energy metastable compounds whose …

Excited state non-adiabatic dynamics of large photoswitchable molecules using a chemically transferable machine learning potential

S Axelrod, E Shakhnovich… - Nature …, 2022 - nature.com
Light-induced chemical processes are ubiquitous in nature and have widespread
technological applications. For example, photoisomerization can allow a drug with a photo …

Upconverting nanocarriers enable triggered microtubule inhibition and concurrent ferroptosis induction for selective treatment of triple-negative breast cancer

J Zhu, P Dai, F Liu, Y Li, Y Qin, Q Yang, R Tian… - Nano …, 2020 - ACS Publications
Despite the resistance of triple-negative breast cancer (TNBC) to targeted hormone therapy,
the discovery of azobenzene combretastatin A4 (Azo-CA4) provides therapeutic …

Visible Light Switching of a BF2-Coordinated Azo Compound

Y Yang, RP Hughes, I Aprahamian - Journal of the American …, 2012 - ACS Publications
Here we report the synthesis and characterization of a BF2–azo complex that can be
induced to isomerize without the need of deleterious UV light. The complexation of the azo …

Structure property analysis of the solution and solid-state properties of bistable photochromic hydrazones

B Shao, H Qian, Q Li, I Aprahamian - Journal of the American …, 2019 - ACS Publications
The development of new photochromic compounds and the optimization of their
photophysical and switching properties are prerequisites for accessing new functions and …

A Light‐Triggered Synthetic Nanopore for Controlling Molecular Transport Across Biological Membranes

D Offenbartl‐Stiegert, A Rottensteiner… - Angewandte …, 2022 - Wiley Online Library
Controlling biological molecular processes with light is of interest in biological research and
biomedicine, as light allows precise and selective activation in a non‐invasive and non‐toxic …

Thermal half-lives of azobenzene derivatives: Virtual screening based on intersystem crossing using a machine learning potential

S Axelrod, E Shakhnovich… - ACS Central …, 2023 - ACS Publications
Molecular photoswitches are the foundation of light-activated drugs. A key photoswitch is
azobenzene, which exhibits trans–cis isomerism in response to light. The thermal half-life of …