Genetics of SLE: mechanistic insights from monogenic disease and disease-associated variants

CG Vinuesa, N Shen, T Ware - Nature Reviews Nephrology, 2023 - nature.com
The past few years have provided important insights into the genetic architecture of systemic
autoimmunity through aggregation of findings from genome-wide association studies …

The interplay between immune and metabolic pathways in kidney disease

L Qu, B Jiao - Cells, 2023 - mdpi.com
Kidney disease is a significant health problem worldwide, affecting an estimated 10% of the
global population. Kidney disease encompasses a diverse group of disorders that vary in …

Th1-related transcription factors and cytokines in systemic lupus erythematosus

YY Tang, DC Wang, YY Chen, WD Xu… - Frontiers in …, 2023 - frontiersin.org
Systemic lupus erythematosus (SLE) is an inflammatory disorder related to immunity
dysfunction. The Th1 cell family including Th1 cells, transcription factor T-bet, and related …

Increase in double negative B lymphocytes in patients with systemic lupus erythematosus in remission and their correlation with early differentiated T lymphocyte …

E Moysidou, G Lioulios, M Christodoulou… - Current Issues in …, 2023 - mdpi.com
B and T lymphocytes demonstrate important alterations in patients with systemic lupus
erythematous (SLE), with a significant upregulation of double negative (DN) B cells. The aim …

Novel B-cell subsets as potential biomarkers in idiopathic inflammatory myopathies: insights into disease pathogenesis and disease activity

RF Reyes-Huerta, V Mandujano-López… - Journal of Leukocyte …, 2024 - academic.oup.com
Idiopathic inflammatory myopathies are a heterogeneous group of rare autoimmune
disorders characterized by progressive muscle weakness and the histopathologic findings of …

SAP-expressing T peripheral helper cells identify systemic lupus erythematosus patients with lupus nephritis

Y Gartshteyn, L Geraldino-Pardilla, L Khalili… - Frontiers in …, 2024 - frontiersin.org
Introduction T follicular (TFH) and peripheral helper (TPH) cells have been increasingly
recognized as a pathogenic subset of CD4 T cells in systemic lupus erythematosus (SLE) …

New biomarkers for the diagnosis and treatment of systemic lupus erythematosus

A Perl, N Agmon-Levin, JC Crispín… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus is an autoimmune disease of unknown etiology that primarily
affects females of child-bearing age with various morbidities (1). Mortality of SLE still …

Research progress in systemic lupus erythematosus from 2021 to 2022

YZ Li, XC Wu - Zhongguo Dang dai er ke za zhi= Chinese Journal …, 2023 - europepmc.org
系统性红斑狼疮 (systemic lupus erythematosus, SLE) 是一种累及多器官系统的自身免疫性
疾病, 临床表现复杂多样, 治疗效果和预后异质性大, 给 SLE 的诊断分型及同质性治疗带来了 …

[HTML][HTML] 2021—2022 年度系统性红斑狼疮研究进展盘点

李永珍, 吴小川 - Chinese Journal of Contemporary Pediatrics, 2023 - ncbi.nlm.nih.gov
系统性红斑狼疮( systemic lupus erythematosus, SLE) 是一种累及多器官系统的自身免疫性
疾病, 临床表现复杂多样, 治疗效果和预后异质性大, 给SLE 的诊断分型及同质性治疗带来了 …

[HTML][HTML] Update on novel blood-based biomarkers for lupus nephritis beyond diagnostic approaches

JL Maravillas-Montero… - Revista de investigación …, 2022 - scielo.org.mx
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with a
wide range of clinical presentations. Lupus nephritis (LN) is a frequent complication of SLE …