The interaction between the sympathetic nervous system and the immune system has been
documented over the last several decades. In this review, the neuroanatomical, cellular, and …

Introduction: The worldwide occurrence of burn injuries remains high despite efforts to
reduce injury incidence through public awareness campaigns and improvements in living …

Objective The practice of early burn wound excision and wound closure by immediate
autologous skin or skin substitutes is the preferred treatment in extensive deep partial and …

Abstract Aims Cyclooxygenase-2 (COX-2) and prostaglandin E 2 (PGE 2) are involved in
chronic inflammation observed in chronic lesions. Nonetheless, neither study demonstrated …

Infantile hemangiomas (IHs) are non-malignant, largely cutaneous vascular tumors affecting
approximately 5-10% of children to varying degrees. During the first year of life, these tumors …

BACKGROUND The hypermetabolic state after severe burns is a major problem that can
lead to several pathophysiologic changes and produce multiple sequelae. Adrenergic …

Skin wound healing is a complex process requiring the coordinated, temporal orchestration
of numerous cell types and biological processes to regenerate damaged tissue. Previous …

Catecholamine upregulation is a core pathophysiological feature in critical illness.
Sustained catecholamine β-adrenergic induction produces adverse effects relevant to …

Stress impairs wound healing of cutaneous lesions; however, the mechanism is still unclear.
The aim of this study was to evaluate the effects of rotational stress on cutaneous wound …

Sympathetic nervous system activation and catecholamine release are important events
following injury and infection. The nature and timing of different pathophysiologic insults …