The use of RNA-based treatments in the field of cancer immunotherapy
M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
Microalgae as an efficient vehicle for the production and targeted delivery of therapeutic glycoproteins against SARS-CoV-2 variants
J Dehghani, A Movafeghi, E Mathieu-Rivet… - Marine drugs, 2022 - mdpi.com
Severe acute respiratory syndrome–Coronavirus 2 (SARS-CoV-2) can infect various human
organs, including the respiratory, circulatory, nervous, and gastrointestinal ones. The virus is …
organs, including the respiratory, circulatory, nervous, and gastrointestinal ones. The virus is …
Designing multi-epitope vaccine against Staphylococcus aureus by employing subtractive proteomics, reverse vaccinology and immuno-informatics approaches
Staphylococcus aureus is a deadly human bacterial pathogen that causes a wide variety of
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …
The active lung microbiota landscape of COVID-19 patients through the metatranscriptome data analysis
Introduction: With the outbreak of coronavirus disease 2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the interaction between the host …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the interaction between the host …
Investigation of nonsynonymous mutations in the spike protein of SARS-CoV-2 and its interaction with the ACE2 receptor by molecular docking and MM/GBSA …
RY Aljindan, AM Al-Subaie, AI Al-Ohali… - Computers in biology and …, 2021 - Elsevier
COVID-19 is an infectious and pathogenic viral disease caused by SARS-CoV-2 that leads
to septic shock, coagulation dysfunction, and acute respiratory distress syndrome. The …
to septic shock, coagulation dysfunction, and acute respiratory distress syndrome. The …
Advances of reverse vaccinology for mRNA vaccine design against SARS-CoV-2: a review of methods and tools
mRNA vaccines are a new class of vaccine that can induce potent and specific immune
responses against various pathogens. However, the design of mRNA vaccines requires the …
responses against various pathogens. However, the design of mRNA vaccines requires the …
Morphological characterization of self-amplifying mRNA lipid nanoparticles
The mRNA technology has emerged as a rapid modality to develop vaccines during
pandemic situations with the potential to protect against endemic diseases. The success of …
pandemic situations with the potential to protect against endemic diseases. The success of …
The adjuvant effects on vaccine and the immunomodulatory mechanisms of polysaccharides from traditional Chinese medicine
D Wang, Y Liu, W Zhao - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Vaccination is still the most successful strategy to prevent and control the spread of
infectious diseases by generating an adequate protective immune response. However …
infectious diseases by generating an adequate protective immune response. However …
Engineering and design of promising T-cell-based multi-epitope vaccine candidates against leishmaniasis
Cutaneous leishmaniasis (CL) is a very common parasitic infection in subtropical areas
worldwide. Throughout decades, there have been challenges in vaccine design and …
worldwide. Throughout decades, there have been challenges in vaccine design and …
Self-amplifying mRNA vaccines: Mode of action, design, development and optimization
MM Pourseif, Y Masoudi-Sobhanzadeh, E Azari… - Drug Discovery …, 2022 - Elsevier
Highlights•The mRNA-based vaccines are tunable quality-by-design immunotherapy
modalities for different diseases.•Self-amplifying mRNA (saRNA) vaccines, a kind of mRNA …
modalities for different diseases.•Self-amplifying mRNA (saRNA) vaccines, a kind of mRNA …