The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

How I prevent GVHD in high-risk patients: posttransplant cyclophosphamide and beyond

J Rimando, SR McCurdy, L Luznik - Blood, 2023 - ashpublications.org
Advances in conditioning, graft-versus-host disease (GVHD) prophylaxis and antimicrobial
prophylaxis have improved the safety of allogeneic hematopoietic cell transplantation (HCT) …

Combining post-transplant cyclophosphamide with antithymocyte globulin for graft-versus-host disease prophylaxis in hematological malignancies

R Duléry, E Brissot, M Mohty - Blood Reviews, 2023 - Elsevier
In search of an ideal partner or alternative to conventional immunosuppressive agents,
rabbit anti-thymocyte globulin (ATG) and, more recently, post-transplant cyclophosphamide …

Cytokine release syndrome in the immunotherapy of hematological malignancies: The biology behind and possible clinical consequences

THA Tvedt, AK Vo, Ø Bruserud, H Reikvam - Journal of Clinical Medicine, 2021 - mdpi.com
Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome
characterized by fever and multiple organ dysfunction associated with (i) chimeric antigen …

[HTML][HTML] State of the CAR-T: risk of infections with chimeric antigen receptor T-cell therapy and determinants of SARS-CoV-2 vaccine responses

J Meir, MA Abid, MB Abid - Transplantation and Cellular Therapy, 2021 - Elsevier
Chimeric antigen receptor T cell (CAR-T) therapy has shown unprecedented response rates
in patients with relapsed/refractory (R/R) hematologic malignancies. Although CAR-T …

Cytokine release syndrome after haploidentical hematopoietic cell transplantation: an international multicenter analysis

R Abboud, F Wan, J Mariotti, M Arango… - Bone Marrow …, 2021 - nature.com
Haploidentical related donor transplantation (haplo-HCT) is associated with cytokine
release syndrome (CRS). We conducted a multicenter retrospective study to analyze risk …

Recipient clonal hematopoiesis in allogeneic bone marrow transplantation for lymphoid malignancies

PH Imus, S Pasca, HL Tsai, YM Aljawai… - Blood …, 2024 - ashpublications.org
Allogeneic blood and marrow transplantation (alloBMT) is increasingly being used in older
patients with blood cancer. Aging is associated with an increasing incidence of clonal …

A SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19

L Xia, L Yuan, Y Hu, J Liu, G Hu, R Qi… - Cellular & Molecular …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is
closely associated with coronavirus disease 2019 (COVID-19) severity and lethality …

Peripheral blood haploidentical hematopoietic cell transplantation for patients aged 70 years and over with acute myeloid leukemia or high-risk myelodysplastic …

S Harbi, L Brac de la Perriere, B Bouchacourt… - Bone Marrow …, 2024 - nature.com
Haploidentical stem cell transplantation (Haplo-SCT) using non-myeloablative conditioning
regimen (NMAC) has extended the feasibility of allogeneic transplantation, notably in older …

The many faces of cytokine release syndrome-related coagulopathy

J Wang, J Doran - Clinical Hematology International, 2021 - Springer
Cytokine release syndrome (CRS) has been increasingly recognized in various conditions
including the coronavirus disease 2019 (COVID-19). It is not only associated with systemic …