Horizontal gene transfer and adaptive evolution in bacteria

BJ Arnold, IT Huang, WP Hanage - Nature Reviews Microbiology, 2022 - nature.com
Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …

Prevotella diversity, niches and interactions with the human host

A Tett, E Pasolli, G Masetti, D Ercolini… - Nature Reviews …, 2021 - nature.com
The genus Prevotella includes more than 50 characterized species that occur in varied
natural habitats, although most Prevotella spp. are associated with humans. In the human …

The person-to-person transmission landscape of the gut and oral microbiomes

M Valles-Colomer, A Blanco-Míguez, P Manghi… - Nature, 2023 - nature.com
The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …

[HTML][HTML] Assessment of global health risk of antibiotic resistance genes

Z Zhang, Q Zhang, T Wang, N Xu, T Lu, W Hong… - Nature …, 2022 - nature.com
Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in
the last decade. Many genes can confer resistance, but evaluating the relative health risks of …

[HTML][HTML] A faecal microbiota signature with high specificity for pancreatic cancer

E Kartal, TSB Schmidt, E Molina-Montes… - Gut, 2022 - gut.bmj.com
Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …

[HTML][HTML] A global metagenomic map of urban microbiomes and antimicrobial resistance

D Danko, D Bezdan, EE Afshin, S Ahsanuddin… - Cell, 2021 - cell.com
We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60
cities over 3 years, representing the first systematic, worldwide catalog of the urban …

Microbial evolution and transitions along the parasite–mutualist continuum

GC Drew, EJ Stevens, KC King - Nature Reviews Microbiology, 2021 - nature.com
Virtually all plants and animals, including humans, are home to symbiotic microorganisms.
Symbiotic interactions can be neutral, harmful or have beneficial effects on the host …

Examining horizontal gene transfer in microbial communities

IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

[HTML][HTML] Elevated rates of horizontal gene transfer in the industrialized human microbiome

M Groussin, M Poyet, A Sistiaga, SM Kearney, K Moniz… - Cell, 2021 - cell.com
Industrialization has impacted the human gut ecosystem, resulting in altered microbiome
composition and diversity. Whether bacterial genomes may also adapt to the …

[HTML][HTML] Reconstruction of ancient microbial genomes from the human gut

MC Wibowo, Z Yang, M Borry, A Hübner, KD Huang… - Nature, 2021 - nature.com
Loss of gut microbial diversity,,,,–in industrial populations is associated with chronic
diseases, underscoring the importance of studying our ancestral gut microbiome. However …