Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport
protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation …

Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that acts as
ligand for nuclear RA receptors (RARs), converting them from transcriptional repressors to …

WHO gratefully acknowledges the technical input of the members of the Nutrition Steering
Committee and the Nutrition Guidance Expert Advisory Group, especially the chairs of the …

Retinoids are required for maintaining many essential physiological processes in the body,
including normal growth and development, normal vision, a healthy immune system, normal …

The requirement for vitamin A in reproduction was first recognized in the early 1900's, and its
importance in the eyes of developing embryos was realized shortly after. A greater …

Vitamin A has diverse biological functions. It is transported in the blood as a complex with
retinol binding protein (RBP), but the molecular mechanism by which vitamin A is absorbed …

Retinoids, the active metabolites of vitamin A, regulate complex gene networks involved in
vertebrate morphogenesis, growth, cellular differentiation and homeostasis. Studies …

It is well established that chylomicron remnant (dietary) vitamin A is taken up from the
circulation by hepatocytes, but more than 80% of the vitamin A in the liver is stored in hepatic …

The blood–brain barrier (BBB) is crucial in the maintenance of a controlled environment
within the brain to safeguard optimal neuronal function. The endothelial cells (ECs) of the …

Vitamin A is an essential nutrient required throughout life. Through its various metabolites,
vitamin A sustains fetal development, immunity, vision, and the maintenance, regulation, and …