Estradiol, either from peripheral or central origin, activates multiple molecular
neuroprotective and neuroreparative responses that, being mediated by estrogen receptors …

Neurologic complications are commonly regarded as irreversible impairments that stem from
limited potential of regeneration of the central nervous system (CNS). On the other side, the …

The nervous system is a target and a source of steroids. Neuroactive steroids are steroids
that target neurons and glial cells. They include hormonal steroids originated in the …

Ischemia-reperfusion injury (I/R injury) is a common feature of ischemic stroke which occurs
when blood supply is restored after a period of ischemia. Although stroke is an important …

The brain is one of the main organs affected by hypoxia and reoxygenation in the neonatal
period and one of the most vulnerable to oxidative stress. Hypoxia/ischemia and …

Objective Progressive supranuclear palsy (PSP) is a 4R‐tauopathy showing heterogeneous
tau cytopathology commencing in the globus pallidus (GP) and the substantia nigra (SN) …

Traumatic brain injury (TBI) is a major cause of morbidity and mortality among young
individuals worldwide. Understanding the pathophysiology of neurotrauma is crucial for the …

High concentrations of palmitic acid in plasma increase both the inflammation associated
with obesity and the susceptibility to develop a neurodegenerative event. In the brain, the …

Purpose Glial fibrillary acidic protein (GFAP) and neuroglobin (NGB) are important
biomarkers of cerebral hypoxia. For this reason, an attempt was made to assess their …

Neurodegenerative diseases, such as Parkinson and Alzheimer, are among the main public
health issues in the world due to their effects on life quality and high mortality rates. Although …