Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Highlights•Pathways controlling melatonin secretion are complex.•There are various causes
of melatonin disturbance.•Evaluation of melatonin secretion clinically requires long time …

In this study, we aimed to evaluate the anti-inflammatory and anti-apoptotic effects of
melatonin (MLT) on neuropathic pain (NP)-induced anxiety and depression in a rat model …

Diabetes and diabetic complications are considered as leading causes of both morbidity
and mortality in the world. Unfortunately, routine medical treatments used for affected …

Diabetic peripheral neuropathy is one of the most common microvascular complications that
occurs with both type 1 and type 2 diabetes mellitus. It has a significant negative impact on …

The peripheral nervous system is one of many organ systems that can be profoundly
impacted in diabetes mellitus. Diabetic peripheral neuropathy has a significant negative …

Abstract Type 2 diabetes mellitus (DM2) is a chronic disease characterised by variable
degrees of insulin resistance and impaired insulin secretion. Besides, several pieces of …

Backgrounds: Diabetes can cause diabetic neuropathy (DN), a nerve injury. High blood
sugar (glucose) levels can harm nerves all over your body. The nerves in your legs and feet …

Purpose The trial aimed to investigate the effectiveness of exogenous melatonin as an
adjuvant to pregabalin for relief of pain in patients suffering from painful diabetic neuropathy …

In the present study, we investigate the role of Date Seed Extract (DSE) in protection against
cerebral ischemic damages. Focal cerebral ischemia was induced by using Middle Cerebral …