Trivalent glycoprotein subunit vaccine prevents neonatal herpes simplex virus mortality and morbidity
CD Patel, SA Taylor, J Mehrbach, S Awasthi… - Journal of …, 2020 - Am Soc Microbiol
Herpes simplex virus (HSV) can cause severe infection in neonates leading to mortality and
lifelong morbidity. Prophylactic approaches, such as maternal immunization, could prevent …
lifelong morbidity. Prophylactic approaches, such as maternal immunization, could prevent …
Using split luciferase assay and anti-Herpes Simplex Virus glycoprotein monoclonal antibodies to predict a functional binding site between gD and gH/gL
D Atanasiu, WT Saw, TM Cairns, RJ Eisenberg… - Journal of …, 2021 - Am Soc Microbiol
Herpes simplex virus (HSV) entry and cell-cell fusion require glycoproteins gD, gH/gL, and
gB. HSV entry begins with gD binding its receptor (nectin-1), which then activates gH/gL to …
gB. HSV entry begins with gD binding its receptor (nectin-1), which then activates gH/gL to …
Antiviral CD19+CD27+ Memory B Cells Are Associated with Protection from Recurrent Asymptomatic Ocular Herpesvirus Infection
NR Dhanushkodi, S Prakash, R Srivastava… - Journal of …, 2022 - Am Soc Microbiol
Reactivation of herpes simplex virus 1 (HSV-1) from latently infected neurons of the
trigeminal ganglia (TG) leads to blinding recurrent herpetic disease in symptomatic (SYMP) …
trigeminal ganglia (TG) leads to blinding recurrent herpetic disease in symptomatic (SYMP) …
Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity
Neonatal herpes simplex virus (nHSV) infections often result in significant mortality and
neurological morbidity despite antiviral drug therapy. Maternally transferred herpes simplex …
neurological morbidity despite antiviral drug therapy. Maternally transferred herpes simplex …