Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …

Both mitochondrial dysfunction and neuroinflammation are implicated in neurodegeneration
and neurodegenerative diseases. Accumulating evidence shows multiple links between …

Background Neuroinflammation has an important role in the pathophysiology of migraine,
which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight …

Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which
seriously threatens the quality of patients' life, especially the older people. Accumulating …

The acetylcholinesterase inhibitors donepezil and rivastigmine have been used as
therapeutic drugs for Alzheimer's disease (AD), but their effects on LPS-and Aβ-induced …

Sevoflurane is one of the most widely used anesthetics for the induction and maintenance of
general anesthesia in surgical patients. Sevoflurane treatment may increase the incidence …

Postoperative cognitive dysfunction (POCD), as one of the common postoperative
complications, mainly occurs after surgery and anesthesia, especially in the elderly. It refers …

Mesenchymal stromal/stem cells (MSCs) perform their therapeutic effects through various
mechanisms, including their ability to differentiate, producing different growth factors …

Cerebrovascular diseases are pathological conditions involving impaired blood flow in the
brain, primarily including ischaemic stroke, intracranial haemorrhage, and subarachnoid …

Neuroinflammatory and neurodegenerative diseases are a major public health problem
worldwide, especially with the increase of life-expectancy observed during the last decades …