The mosquito midgut stages of malaria parasites are crucial for establishing an infection in
the insect vector and to thus ensure further spread of the pathogen. Parasite development in …

The malaria parasite life cycle alternates between two hosts: a vertebrate and the female
Anopheles mosquito vector. Cell division, proliferation, and invasion are essential for …

Transmission of malaria-causing parasites to mosquitoes relies on the production of
gametocyte stages and their development into gametes. These stages display various …

Malaria-causing parasites of the Plasmodium genus undergo multiple developmental
phases in the human and the mosquito hosts, regulated by various post-translational …

The development of malaria parasites throughout their various life cycle stages is
coordinated by changes in gene expression. We previously showed that the three …

Organ growth involves the coordination of cell proliferation and cell growth with
differentiation. Endoreduplication is correlated with the onset of cell differentiation and with …

Faithful chromosome segregation of 8 duplicated haploid genomes into 8 daughter gametes
is essential for male gametogenesis and mosquito transmission of Plasmodium …

Recent reviews (Feachem et al.; Alonso et al.) have concluded that in order to have a
sustainable impact on the global burden of malaria, it is essential that we knowingly reduce …

Cell cycle transitions are generally triggered by variation in the activity of cyclin-dependent
kinases (CDKs) bound to cyclins. Malaria-causing parasites have a life cycle with unique …

Mitosis is an important process in the cell cycle required for cells to divide. Never in mitosis
(NIMA)-like kinases (NEKs) are regulators of mitotic functions in diverse organisms …