[HTML][HTML] Cancer-related cognitive impairment: an update on state of the art, detection, and management strategies in cancer survivors

M Lange, F Joly, J Vardy, T Ahles, M Dubois, L Tron… - Annals of …, 2019 - Elsevier
Background Advances in diagnostic and therapeutic strategies in oncology have
significantly increased the chance of survival of cancer patients, even those with metastatic …

Mitigating long-term and delayed adverse events associated with cancer treatment: implications for survivorship

MB Lustberg, NM Kuderer, A Desai… - Nature Reviews …, 2023 - nature.com
Despite the importance of chemotherapy-associated adverse events in oncology practice
and the broad range of interventions available to mitigate them, limited systematic efforts …

[HTML][HTML] Apolipoprotein E in lipid metabolism and neurodegenerative disease

LG Yang, ZM March, RA Stephenson… - Trends in Endocrinology & …, 2023 - cell.com
Dysregulation of lipid metabolism has emerged as a central component of many
neurodegenerative diseases. Variants of the lipid transport protein, apolipoprotein E …

The role of APOE4 in disrupting the homeostatic functions of astrocytes and microglia in aging and Alzheimer's disease

CG Fernandez, ME Hamby, ML McReynolds… - Frontiers in aging …, 2019 - frontiersin.org
APOE4 is the greatest genetic risk factor for late-onset Alzheimer's disease (AD), increasing
the risk of developing the disease by 3-fold in the 14% of the population that are carriers …

NCCN guidelines® insights: survivorship, version 1.2023: featured updates to the NCCN guidelines

T Sanft, A Day, S Ansbaugh, S Armenian… - Journal of the National …, 2023 - jnccn.org
The NCCN Guidelines for Survivorship are intended to help healthcare professionals
address the complex and varied needs of cancer survivors. The NCCN Guidelines provide …

Cancer-related accelerated ageing and biobehavioural modifiers: a framework for research and clinical care

JE Carroll, JE Bower, PA Ganz - Nature Reviews Clinical Oncology, 2022 - nature.com
A growing body of evidence indicates that patients with cancer who receive cytotoxic
treatments (such as chemotherapy or radiotherapy) have an increased risk of accelerated …

Measuring aging and identifying aging phenotypes in cancer survivors

JL Guida, TA Ahles, D Belsky, J Campisi… - JNCI: Journal of the …, 2019 - academic.oup.com
Observational data have shown that some cancer survivors develop chronic conditions like
frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at a …

Cellular mechanisms and treatments for chemobrain: insight from aging and neurodegenerative diseases

LD Nguyen, BE Ehrlich - EMBO molecular medicine, 2020 - embopress.org
Chemotherapy is a life‐saving treatment for cancer patients, but also causes long‐term
cognitive impairment, or “chemobrain”, in survivors. However, several challenges, including …

Loneliness and mental health during the COVID‐19 pandemic in older breast cancer survivors and noncancer controls

KE Rentscher, X Zhou, BJ Small, HJ Cohen… - Cancer, 2021 - Wiley Online Library
Background The coronavirus disease 2019 (COVID‐19) pandemic has had wide‐ranging
health effects and increased isolation. Older with cancer patients might be especially …

Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological …

SJ Mayo, M Lustberg, HM Dhillon… - Supportive Care in …, 2021 - Springer
Cancer-related cognitive impairment (CRCI) is commonly experienced by individuals with
non-central nervous system cancers throughout the disease and treatment trajectory. CRCI …