Multi-omics data analyses construct TME and identify the immune-related prognosis signatures in human LUAD

Y Zhang, M Yang, DM Ng, M Haleem, T Yi, S Hu… - … Therapy-Nucleic Acids, 2020 - cell.com
Lung cancer has been the focus of attention for many researchers in recent years for the
leading contribution to cancer-related death worldwide, in which lung adenocarcinoma …

Targeting breast cancer through its microenvironment: current status of preclinical and clinical research in finding relevant targets

HH Nienhuis, SBM Gaykema… - Pharmacology & …, 2015 - Elsevier
It is increasingly evident that not only breast cancer cells, but also the tissue embedding
these cells: the tumor microenvironment, plays an important role in tumor progression …

Omic-profiling in breast cancer metastasis to bone: implications for mechanisms, biomarkers and treatment

SL Wood, JA Westbrook, JE Brown - Cancer treatment reviews, 2014 - Elsevier
Despite well-recognised advances in breast cancer treatment, there remain substantial
numbers of patients who develop metastatic disease, of which up to 70% involves spread to …

[HTML][HTML] The immunotoxicity of decabromodiphenyl ether (BDE-209) on broiler chicks by transcriptome profiling analysis

L Cheng, Q Rao, Q Zhang, W Song, S Guan… - Ecotoxicology and …, 2022 - Elsevier
Abstract Decabromodiphenyl ether (BDE-209) has drawn significant attention due to its
suppression of immune functions in animals and even humans. In order to explore the …

Identification of NOG as a Specific Breast Cancer Bone Metastasis-supporting Gene*♦

M Tarragona, M Pavlovic, A Arnal-Estapé… - Journal of Biological …, 2012 - ASBMB
Metastasis requires numerous biological functions that jointly provide tumor cells from a
primary site to seed and colonize a distant organ. Some of these activities are selected for in …

[HTML][HTML] Analysis of microarray-identified genes and microRNAs associated with drug resistance in ovarian cancer

J Zou, F Yin, Q Wang, W Zhang, L Li - International journal of …, 2015 - ncbi.nlm.nih.gov
Analysis of microarray-identified genes and microRNAs associated with drug resistance in
ovarian cancer - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Permanent pro-tumorigenic shift in adipose tissue-derived mesenchymal stromal cells induced by breast malignancy

J Plava, M Cihova, M Burikova, M Bohac, M Adamkov… - Cells, 2020 - mdpi.com
During cancer progression, breast tumor cells interact with adjacent adipose tissue, which
has been shown to be engaged in cancer aggressiveness. However, the tumor-directed …

Breast tumor microenvironment can transform naive mesenchymal stem cells into tumor-forming cells in nude mice

PM Wörner, DJ Schächtele, Z Barabadi… - Stem cells and …, 2019 - liebertpub.com
How mesenchymal stem cells (MSCs) interact with tumor cells and promote tumor growth is
not well understood. In this study, we demonstrate that when naive MSCs and malignant …

[HTML][HTML] BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation

MW Pickup, LD Hover, ER Polikowsky, A Chytil… - Molecular Oncology, 2015 - Elsevier
Abstract Bone Morphogenetic Protein (BMP) receptors mediate a diverse range of signals to
regulate both development and disease. BMP activity has been linked to both tumor …

[HTML][HTML] Downregulation of tumor suppressor gene ribonuclease T2 and gametogenetin binding protein 2 is associated with drug resistance in ovarian cancer

F Yin, L Liu, X Liu, G Li, L Zheng, D Li… - Oncology …, 2014 - spandidos-publications.com
Abstract Ribonuclease T2 (RNASET2) and gametogenetin binding protein 2 (GGNBP2) are
tumor suppressor genes whose expression is downregulated in ovarian and other types of …