The role of the ghrelin system in drug addiction

LJ Zallar, M Farokhnia, BJ Tunstall… - International review of …, 2017 - Elsevier
In the past years, a significant volume of research has implicated the appetitive hormone
ghrelin in the mechanisms underlying drug use and addiction. From a neuroscientific …

Nicotine and energy balance: A review examining the effect of nicotine on hormonal appetite regulation and energy expenditure

A Schwartz, N Bellissimo - Appetite, 2021 - Elsevier
Nicotine has been shown to decrease appetite, food intake (FI) and body weight, but the
mechanisms are unclear. The purpose of this review was to examine research on the effects …

The intriguing ligand-dependent and ligand-independent actions of the growth hormone secretagogue receptor on reward-related behaviors

MP Cornejo, ER Mustafá, F Barrile, D Cassano… - Neuroscience & …, 2021 - Elsevier
The growth hormone secretagogue receptor (GHSR) is a G-protein-coupled receptor
(GPCR) highly expressed in the brain, and also in some peripheral tissues. GHSR activity is …

Emerging role of mitochondrial DAMPs, aberrant mitochondrial dynamics and anomalous mitophagy in gut mucosal pathogenesis

S Mazumder, S Bindu, R De, S Debsharma… - Life Sciences, 2022 - Elsevier
Gastroduodenal inflammation and ulcerative injuries are increasing due to expanding socio-
economic stress, unhealthy food habits-lifestyle, smoking, alcoholism and usage of …

[HTML][HTML] Acute nicotine intake increases feeding behavior through decreasing glucagon signaling in dependent male and female rats

K Shankar, J Ramborger, S Bonnet-Zahedi… - Hormones and …, 2024 - Elsevier
Chronic use of nicotine is known to dysregulate metabolic signaling through altering
circulating levels of feeding-related hormones, contributing to the onset of disorders like type …

The role of ghrelin/GHS-R1A signaling in nonalcohol drug addictions

M Sustkova-Fiserova, C Charalambous… - International Journal of …, 2022 - mdpi.com
Drug addiction causes constant serious health, social, and economic burden within the
human society. The current drug dependence pharmacotherapies, particularly relapse …

Neurobiological mechanisms of nicotine's effects on feeding and body weight

Y Li, J Mao, G Chai, R Zheng, X Liu, J Xie - Neuroscience & Biobehavioral …, 2025 - Elsevier
Nicotine, a neuroactive substance in tobacco products, has been widely studied for its
effects on feeding and body weight, mostly focusing on the involvement of nervous system …

[HTML][HTML] Exposure to nicotine regulates prostaglandin E2 secretion and autophagy of granulosa cells to retard follicular maturation in mammals

X Zhou, Y He, H Quan, J Yang, S Li, Y Jiang, J Li… - Ecotoxicology and …, 2024 - Elsevier
Exposure to nicotine by cigarette smoking have shown strongly defectives on the
physiological function of ovaries, which in turn leads to disorders of fertility in women …

Effect of nicotine on placental ischemia-induced complement activation and hypertension in the rat

CF Laule, CR Wing, EJ Odean, JA Wilcox… - Journal of …, 2017 - Taylor & Francis
Preeclampsia is a pregnancy-specific condition manifested by new-onset maternal
hypertension with systemic inflammation, including increased innate immune system …

A population-based investigation of the association between alcohol intake and serum total ghrelin concentrations among cigarette-smoking, non-alcohol-dependent …

M Farokhnia, G Murphy, SJ Weinstein, NN Shah… - Drug and alcohol …, 2021 - Elsevier
Background Ghrelin plays significant roles in regulating appetite, food intake, and
metabolism. Furthermore, the ghrelin system is increasingly being studied in relation to …