ABC transporters are ubiquitous in the human body and are responsible for the efflux of
drugs. They are present in the placenta, intestine, liver and kidney, which are the major …

Biomarkers are biological molecules found in body fluids or tissues, which can be
considered as indications of a normal or abnormal process, or of a condition or disease …

Acute lymphoblastic leukemia (ALL) is the most prevalent cancer among children, and
multidrug efflux mediated by overexpression of ABC transporters is the major impediment to …

Drug transporters are integral membrane proteins that play a critical role in drug disposition
by affecting absorption, distribution, and excretion. They translocate drugs, as well as …

Expression of long non-coding RNA KIAA0125 has been incorporated in various gene
expression signatures for prognostic prediction in acute myeloid leukemia (AML) patients …

Ovarian cancer, one of the deadliest malignancies in female cancer patients, is
characterized by recurrence and poor response to cytotoxic chemotherapies. Fewer than …

The expression of ATP-binding cassette transporter (ABC transporters) has been reported in
various tissues such as the lung, liver, kidney, brain and intestine. These proteins account …

Acute lymphoblastic leukemia (ALL) is one of the most frequent hematological malignancies
in children, representing approximately 25% of all pediatric cancers. Despite striking …

Purpose Based on the poor prognosis of drug resistance in pediatric acute lymphoblastic
leukemia (ALL) and adverse effects of chemotherapy, this study was aimed to evaluate the …

T-cell acute lymphoblastic leukemia (T-ALL) is the most prevalent malignancy in children.
Long non-coding RNAs are being found to have relevance to the pathogenesis of pediatric T …