Medicinal Potential of Garcinia Species and Their Compounds

BLS Espirito Santo, LF Santana, WH Kato Junior… - Molecules, 2020 - mdpi.com
Garcinia is a genus of Clusiaceae, distributed throughout tropical Asia, Africa, New
Caledonia, Polynesia, and Brazil. Garcinia plants contain a broad range of biologically …

Endoplasmic reticulum stress: a master regulator of metabolic syndrome

S Mohan, L Brown, P Ayyappan - European Journal of Pharmacology, 2019 - Elsevier
Endoplasmic reticulum (ER) stress, a change in the ER homeostasis, leads to initiation of the
unfolded protein response (UPR). The primary functions of the UPR are to restore the ER's …

Garcinia cambogia Ameliorates Non-Alcoholic Fatty Liver Disease by Inhibiting Oxidative Stress-Mediated Steatosis and Apoptosis through NRF2-ARE Activation

JH Han, MH Park, CS Myung - Antioxidants, 2021 - mdpi.com
Excessive free fatty acids (FFAs) causes reactive oxygen species (ROS) generation and non-
alcoholic fatty liver disease (NAFLD) development. Garcinia cambogia (G. cambogia) is …

Inverse relationship between body mass index and mitochondrial oxidative phosphorylation capacity in human subcutaneous adipocytes

B Fischer, T Schöttl, C Schempp… - American Journal …, 2015 - journals.physiology.org
Obesity is characterized by a substantial increase in adipose tissue that may contribute to
energy balance. Recently, obesity was suggested to be associated with impaired …

Inhibition of the RPS6KA1/FoxO1 signaling axis by hydroxycitric acid attenuates HFD-induced obesity through MCE suppression

HW Lee, R Karki, JH Han - Phytomedicine, 2024 - Elsevier
Background Because obesity is associated with a hyperplasia-mediated increase in adipose
tissue, inhibiting cell proliferation during mitotic clonal expansion (MCE) is a leading strategy …

Therapeutic Effect of Garcinia cambogia Extract and Hydroxycitric Acid Inhibiting Hypoxia-Inducible Factor in a Murine Model of Age-Related Macular Degeneration

M Ibuki, C Shoda, Y Miwa, A Ishida, K Tsubota… - International journal of …, 2019 - mdpi.com
Background: Age-related macular degeneration (AMD) is the leading cause of blindness
and can be classified into two types called atrophic AMD (dry AMD) and neovascular AMD …

[HTML][HTML] (-)-Hydroxycitric acid reduced lipid droplets accumulation via decreasing acetyl-coa supply and accelerating energy metabolism in cultured primary chicken …

L Li, M Peng, C Ge, L Yu, H Ma - Cellular Physiology and Biochemistry, 2017 - karger.com
Background/Aims:(-)-Hydroxycitric acid (HCA) had been shown to suppress fat accumulation
in animals and humans, while the underlying biochemical mechanism is not fully …

Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1α Pathway

ZL Lu, CK Song, SS Zou, SZ Pan, K Lai, N Li… - Current Issues in …, 2023 - mdpi.com
Lung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary
diseases and surgical procedures, including lung resections and transplantation. LIRI can …

Medicinal Potential of Garcinia Species and Their Compounds.

E Santo BLSD, LF Santana, KJ WH… - Molecules (Basel …, 2020 - europepmc.org
Garcinia is a genus of Clusiaceae, distributed throughout tropical Asia, Africa, New
Caledonia, Polynesia, and Brazil. Garcinia plants contain a broad range of biologically …

Capillary zone electrophorsis for the analysis of naturally occurring 2‐hydroxycitric acids and their lactones

BL Abhijith, M Mohan, D Joseph… - Journal of separation …, 2017 - Wiley Online Library
A simple capillary zone electrophoresis method with direct ultraviolet detection has been
developed for the analysis of naturally occurring diastereomeric 2‐hydroxycitric acid …