Nanodrugs systems for therapy and diagnosis of esophageal cancer

L Zhang, X Li, G Yue, L Guo, Y Hu, Q Cui… - … in Bioengineering and …, 2023 - frontiersin.org
With the increasing incidence of esophageal cancer, its diagnosis and treatment have
become one of the key issues in medical research today. However, the current diagnostic …

Research Progress on the predicting factors and coping strategies for postoperative recurrence of esophageal cancer

Y Zhang, Y Zhang, L Peng, L Zhang - Cells, 2022 - mdpi.com
Esophageal cancer is one of the malignant tumors with poor prognosis in China. Currently,
the treatment of esophageal cancer is still based on surgery, especially in early and mid …

The role of MiRNA in cancer: pathogenesis, diagnosis, and treatment

E Uzuner, GT Ulu, SB Gürler, Y Baran - miRNomics: MicroRNA Biology …, 2022 - Springer
Cancer is also determined by the alterations of oncogenes and tumor suppressor genes.
These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers …

Network analysis of miRNA targeting m6A-related genes in patients with esophageal cancer

L Li, R Xie, Q Wei - PeerJ, 2021 - peerj.com
Background We investigated the miRNA-m6A related gene network and identified a miRNA-
based prognostic signature in patients with esophageal cancer using integrated genomic …

MiR-25-3p targets PTEN to regulate the migration, invasion, and apoptosis of esophageal cancer cells via the PI3K/AKT pathway

L Zhang, Z Tong, Z Sun, G Zhu, E Shen… - Bioscience …, 2020 - portlandpress.com
Background: Esophageal cancer (EC) is one of the most common malignant tumors of the
digestive system. MiR-25-3p was proved to be a biomarker for the diagnosis and treatment …

Recent development of bioinformatics tools for microRNA target prediction

MS Khatun, MA Alam, W Shoombuatong… - Current medicinal …, 2022 - ingentaconnect.com
MicroRNAs (miRNAs) are central players that regulate the post-transcriptional processes of
gene expression. Binding of miRNAs to target mRNAs can repress their translation by …

Regulatory roles of noncoding RNAs in the progression of gastrointestinal cancers and health disparities

A Kulkarni, S Gayathrinathan, S Nair, A Basu… - Cells, 2022 - mdpi.com
Annually, more than a million individuals are diagnosed with gastrointestinal (GI) cancers
worldwide. With the advancements in radio-and chemotherapy and surgery, the survival …

MicroRNA‑200a promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through extensive target genes

B Yang, Y Liu, L Li, H Deng… - Molecular medicine …, 2020 - spandidos-publications.com
Despite investigations into microRNA (miRNA) expression in esophageal cancer (EC)
tissue, miRNAs that participate in EC pathogenesis and their subsequent mechanisms of …

CEACAM Gene Family Mutations Associated With Inherited Breast Cancer Risk – A Comparative Oncology Approach to Discovery

ALW Huskey, I McNeely, ND Merner - Frontiers in Genetics, 2021 - frontiersin.org
Introduction Recent studies comparing canine mammary tumors (CMTs) and human breast
cancers have revealed remarkable tumor similarities, identifying shared expression profiles …

miR-335-5p Inhibits EMT and PI3K/AKT Pathways via MARCH8

A Bano, G Suyal, A Saraya, R Sharma - Indian Journal of Clinical …, 2024 - Springer
Ubiquitination is a highly conserved process that regulates protein stability by post-
translational modification. Membrane-associated RING-CH (MARCH) proteins belong to a …