Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

The tubers and roots of Aconitum (Ranunculaceae) are widely used as heart medicine or
analgesic agents for the treatment of coronary heart disease, chronic heart failure …

Hidradenitis suppurativa (HS) is a highly prevalent, morbid inflammatory skin disease with
limited treatment options. The major cell types and inflammatory pathways in skin of patients …

In immunology, the discovery of regulatory T (Treg) cells was a major breakthrough. Treg
cells play a key role in pregnancy maintenance, in the prevention of autoimmune responses …

Inflammation causes severe dysregulation of organ functions, via the development of
oxidative stress and inflammation damage. Polyphenol compounds found in green tea …

The concept that a subset of T cells exists that specifically suppresses immune responses
was originally proposed over 50 years ago. It then took the next 30 years to solidify the …

We used functional-omics angles and examined transcriptomic heterogeneity in CD4+
Foxp3+ regulatory T cells (Treg) from spleen (s-Treg), lymph nodes (LN-Treg), intestine (int …

Interleukin (IL)-18, a member of the IL-1 family of alarmins, is abundantly released in the
lungs following influenza A (IAV) infections yet its role in orchestrating the local adaptive …

During infections, the timings of effector differentiation of pulmonary immune responses are
of paramount importance, as pathogen persistence and unsuppressed inflammation can …

Foxp3+ regulatory T (Treg) cells are the major gatekeepers of the immune system for the
maintenance of self-tolerance and immune homeostasis. Treg cell development rests on the …