Addressing the multiscale organization of the brain, which is fundamental to the dynamic
repertoire of the organ, remains challenging. In principle, it should be possible to model …

The recent construction of brain-wide gene expression atlases, which measure the
transcriptional activity of thousands of genes in multiple anatomical locations, has made it …

We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

The human brain is a complex, adaptive system comprised of billions of cells with trillions of
connections. The interactions between the elements of the system oppose this seemingly …

Robots may one day rule the world, but what is a robot-ruled Earth like? Many think the first
truly smart robots will be brain emulations or ems. Scan a human brain, then run a model …

The structures of dendrites and axons form the basis for the connectivity of neural network,
but their precise relationship at single-neuron level remains unclear. Here we report the …

The neurobiology of schizophrenia involves multiple facets of pathophysiology, ranging from
its genetic basis over changes in neurochemistry and neurophysiology, to the systemic level …

The wiring architecture of neuronal networks is assumed to be a strong determinant of their
dynamical computations. An ongoing effort in neuroscience is therefore to generate …

How is the massive dimensionality and complexity of the microscopic constituents of the
nervous system brought under sufficiently tight control so as to coordinate adaptive …

Recent demonstrations of human brain organoid transplantation in rodents have
accentuated ethical concerns associated with these entities, especially as they relate to …