Application of Single Extracellular Vesicle Analysis Techniques

J Zhu, F Wu, C Li, J Mao, Y Wang, X Zhou… - International Journal …, 2023 - Taylor & Francis
Extracellular vesicles (EVs) are lipid containers that are actively released by cells and
contain complex molecular cargoes. These cargoes include abundant material such as …

Clinical relevance of extracellular vesicles in hematological neoplasms: from liquid biopsy to cell biopsy

S Trino, D Lamorte, A Caivano, L De Luca, A Sgambato… - Leukemia, 2021 - nature.com
In the era of precision medicine, liquid biopsy is becoming increasingly important in
oncology. It consists in the isolation and analysis of tumor-derived biomarkers, including …

Extracellular vesicle-associated DNA: ten years since its discovery in human blood

T Tsering, A Nadeau, T Wu, K Dickinson… - Cell Death & …, 2024 - nature.com
Extracellular vesicles (EVs) have emerged as key players in intercellular communication,
facilitating the transfer of crucial cargo between cells. Liquid biopsy, particularly through the …

Extracellular vesicle-mediated crosstalk between pancreatic cancer and stromal cells in the tumor microenvironment

Y Li, W Zhao, Y Wang, H Wang, S Liu - Journal of Nanobiotechnology, 2022 - Springer
Pancreatic ductal adenocarcinoma (PDAC) interacts closely with the tumor
microenvironment (TME). The TME is remodeled by crosstalk between pancreatic cancer …

EV‐ADD, a database for EV‐associated DNA in human liquid biopsy samples

T Tsering, M Li, Y Chen, A Nadeau… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) play a key role in cellular communication both in physiological
conditions and in pathologies such as cancer. Emerging evidence has shown that EVs are …

Single molecule localization microscopy for studying small extracellular vesicles

J Ghanam, VK Chetty, X Zhu, X Liu, M Gelléri, L Barthel… - Small, 2023 - Wiley Online Library
Small extracellular vesicles (sEVs) are 30–200 nm nanovesicles enriched with unique
cargoes of nucleic acids, lipids, and proteins. sEVs are released by all cell types and have …

Extracellular vesicles: from biomarkers to therapeutic tools

S Bernardi, C Balbi - Biology, 2020 - mdpi.com
Intercellular communication is an essential hallmark of multicellular organisms and can be
mediated through direct cell–cell contact or transfer of secreted molecules. In the last two …

Pregnancy-related extracellular vesicles revisited

CE Condrat, VN Varlas, F Duică, P Antoniadis… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are small vesicles ranging from 20–200 nm to 10 μm in diameter
that are discharged and taken in by many different types of cells. Depending on the nature …

Characteristics and clinical application of extracellular vesicle-derived DNA

JY Hur, KY Lee - Cancers, 2021 - mdpi.com
Simple Summary We reviewed characterization and the role of DNAs derived from
extracellular vesicles focusing on its use for identifying biomarkers. Extracellular vesicles …

DNA in extracellular vesicles: From evolution to its current application in health and disease

J Ghanam, VK Chetty, L Barthel, D Reinhardt… - Cell & Bioscience, 2022 - Springer
Extracellular vesicle (EV) secretion is a highly conserved evolutionary trait in all organisms
in the three domains of life. The packaging and release of EVs appears to be a bulk-flow …