Introduction Ulcerative colitis (UC) is a chronic illness requiring lifelong management that could be enhanced by personalizing care using biomarkers. Areas covered The main …
Precision medicine in immune-mediated inflammatory diseases (IMIDs) requires a cellular understanding of treatment response. We describe a therapeutic atlas for Crohn's disease …
G Caliendo, G D'Elia, J Makker, L Passariello… - Advances in Medical …, 2023 - Elsevier
In this review, we have summarized the existing knowledge of ulcerative colitis (UC) markers based on current literature, specifically, the roles of potential new biomarkers, such as …
K Clarkston, R Karns, AG Jegga… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims We aimed to determine whether a targeted gene expression panel could predict clinical outcomes in paediatric ulcerative colitis [UC] and investigated …
Background A widely used approach for extracting information from gene expression data employs the construction of a gene co-expression network and the subsequent …
A widely used approach for extracting information from gene expression data employ the construction of a gene co-expression network and the subsequent application of algorithms …
K Sinha, S Chakraborty, A Bardhan, R Saha… - medRxiv, 2024 - medrxiv.org
Background Identifying the set of disease-causing genes is crucial for understanding pathogenesis and developing therapies. This is particularly important to understand the …
High-throughput technologies such as DNA microarrays and RNA-seq are used to measure the expression levels of large numbers of genes simultaneously. To support the extraction of …
Understanding the individuality of human brain function and dysfunction requires the integration of data on brain organization across individuals, molecular and systems scales …